SCHEMBL1054428

SCHEMBL1054428

O=C(/C=C\C(=O)OOc1ccccc1)OOc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.43
KDM4E B2RXH2 2/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPT P10636 2/20 0.42
ALOX15 P16050 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 2/20 0.39
F2 P00734 1/20 0.39
THRB P10828 2/20 0.39
HTT P42858 1/20 0.39
MAOB P27338 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.38
LTA4H P09960 1/20 0.38
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 2/20 0.37
NSD2 O96028 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22342516 0.94 HCAR2 (0.51) HCAR2KDM4EHPGDHSD17B10MAPT
SCHEMBL8373834 0.86 KMT2A (0.56) HCAR2MAPTSMN1; SMN2LMNAMAOB
SCHEMBL8373833 0.86 KMT2A (0.56) HCAR2MAPTSMN1; SMN2LMNAMAOB
SCHEMBL385457 0.83 THRB (0.53) KDM4EHPGDHSD17B10MAPTALOX15
SCHEMBL30300800 0.83 THRB (0.53) KDM4EHPGDHSD17B10MAPTALOX15
Ethylene SCHEMBL7650199 0.81 THRB (0.51) KDM4EHPGDHSD17B10MAPTALOX15
SCHEMBL356194 0.78 HPGD (0.57) HCAR2KDM4EHPGDHSD17B10MAPT
SCHEMBL1249384 0.78 HPGD (0.57) HCAR2KDM4EHPGDHSD17B10MAPT
SCHEMBL356193 0.78 HPGD (0.57) HCAR2KDM4EHPGDHSD17B10MAPT
SCHEMBL8731765 0.78 ALOX15 (0.44) HPGDHSD17B10ALOX15LMNAF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731735-A1 METHODS OF REDUCING THE FOAMING OF ACID-BASED CLEANING COMPOSITIONS Reckitt Benckiser Health Limited (GB) 2026-04-29 EP disclosed
EP-4695365-A1 OPTIMIZING THE FLOW CHARACTERISTICS OF LIQUID CLEANING COMPOSITIONS Reckitt Benckiser Health Limited (GB) 2026-02-18 EP disclosed
WO-2024261132-A1 METHODS OF REDUCING THE FOAMING OF ACID-BASED CLEANING COMPOSITIONS Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2024-12-26 WO disclosed
WO-2024213588-A1 OPTIMIZING THE FLOW CHARACTERISTICS OF LIQUID CLEANING COMPOSITIONS Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2024-10-17 WO disclosed
US-10435650-B2 Cleaning composition and method for using the same MILLIKEN & COMPANY (US) 2019-10-08 US disclosed
US-20170260484-A1 CLEANING COMPOSITION AND METHOD FOR USING THE SAME MILLIKEN & COMPANY 2017-09-14 US disclosed
US-20170218310-A1 Laundry Scent Booster COLGATE-PALMOLIVE COMPANY (US) 2017-08-03 US disclosed
US-9688946-B2 Cleaning composition and method for using the same MILLIKEN & COMPANY (US) 2017-06-27 US disclosed
US-8871697-B2 Fragrance delivery GIVAUDAN SA (CH) 2014-10-28 US disclosed
WO-2014092865-A2 CLEANING COMPOSITION AND METHOD FOR USING THE SAME MILLIKEN & COMPANY (US) 2014-06-19 WO disclosed
EP-1706475-A1 FOAMING TWO-COMPONENT HARD SURFACE CLEANING COMPOSITIONS Reckitt Benckiser Inc. (US) 2006-10-04 EP disclosed
US-20060172917-A1 Fragrance delivery GIVAUDAN SA (CH) 2006-08-03 US disclosed
EP-1604000-A1 FRAGRANCE DELIVERY Givaudan SA (CH) 2005-12-14 EP disclosed
WO-2005068595-A1 FOAMING TWO-COMPONENT HARD SURFACE CLEANING COMPOSITIONS RECKITT BENCKISER INC. (US) 2005-07-28 WO disclosed
WO-2005049783-A1 CLEANING COMPOSITIONS RECKITT BENCKISER INC (US) 2005-06-02 WO disclosed
US-6835705-B2 Comprises viscosity-stabilizing amount of tripropylene glycol monomethyl ether, dipropylene glycol monomethyl ether, and sodium dialkyl sulphosuccinate GIVAUDAN SA (CH) 2004-12-28 US disclosed
WO-2004083356-A1 FRAGRANCE DELIVERY GIVAUDAN SA (CH) 2004-09-30 WO disclosed
US-20030008792-A1 Cleaning composition GIVAUDAN SA (CH) 2003-01-09 US disclosed
EP-1264875-A1 Cleaning composition Givaudan SA (CH) 2002-12-11 EP disclosed
US-6228821-B1 CLEANING COMPOSITION COMPRISING INGREDIENTS USEFUL FOR FORMULATING LAUNDRY AND CLEANING COMPOSITIONS, ENZYMES, PERFUME, STABILIZER SELECTED FROM GROUP CONSISTING OF THIOSULFATE, THIOSULFURIC ACID AND MIXTURES THEREOF AMWAY CORPORATION 2001-05-08 US disclosed