Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.66 |
| ▸ | NAAA | Q02083 | 5/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10541442 | 0.88 | CTSL (0.73) | CTSLNAAACTSKCTSS | |
| SCHEMBL10545254 | 0.85 | CTSL (0.65) | CTSLNAAACTSKCTSS | |
| SCHEMBL10544614 | 0.85 | CTSL (0.65) | CTSLNAAACTSKCTSS | |
| SCHEMBL11080515 | 0.83 | CTSK (0.47) | CTSLCTSKCTSSCTSB | |
| SCHEMBL10545323 | 0.82 | CTSK (0.45) | CTSLCTSKCTSSCTSBCTSF | |
| SCHEMBL10545089 | 0.81 | CTSL (0.65) | CTSLNAAACTSKCTSS | |
| SCHEMBL10544954 | 0.81 | CTSL (0.59) | CTSLNAAACTSKCTSS | |
| SCHEMBL7451896 | 0.80 | CTSL (1.00) | CTSLNAAACTSKCTSSCTSB | |
| SCHEMBL7448502 | 0.80 | CTSL (1.00) | CTSLNAAACTSKCTSSCTSB | |
| SCHEMBL10541088 | 0.80 | CTSL (0.65) | CTSLNAAACTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822788-A | MICROBIOCIDES, BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4822790-A | ANTIMICROBIOCIDES OR BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4782147-A | ANTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| US-4675397-A | MICROBIOCIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-06-23 | — | — | US | disclosed |
| US-4665067-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4550105-A | BETA-LACTAMASE INHIBITORS, ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-29 | — | — | US | disclosed |
| EP-0021678-B1 | 1-SULPHO-2-OXOAZETIDINE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 1984-11-07 | — | — | EP | disclosed |
| EP-0021678-A1 | 1-Sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |