SCHEMBL105448

SCHEMBL105448

COC(=O)C(C)CC(Br)C(=O)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.38
CA14 Q9ULX7 1/20 0.38
ZDHHC7 Q9NXF8 1/20 0.36
DGAT1 O75907 1/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA7 P43166 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
POLB P06746 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
CYP2D6 P10635 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9352213 0.87 ZDHHC7 (0.43) CA12CA14ZDHHC7DGAT1CA1
SCHEMBL13613729 0.85 CA14 (0.42) CA12CA14DGAT1CA1CA2
SCHEMBL106430 0.85 ZDHHC7 (0.47) CA12CA14ZDHHC7CA1CA2
SCHEMBL9352351 0.82 KMT2A (0.33) CA12CA14ZDHHC7DGAT1CA1
SCHEMBL4634115 0.81 CA1 (0.38) CA1CA2CA7MEN1KMT2A
SCHEMBL4634114 0.81 CA1 (0.38) CA1CA2CA7MEN1KMT2A
SCHEMBL4385861 0.81 CA1 (0.38) CA1CA2CA7MEN1KMT2A
SCHEMBL22145578 0.80 CA12 (0.33) CA12CA14ZDHHC7DGAT1CA1
SCHEMBL22162338 0.80 CA12 (0.33) CA12CA14ZDHHC7DGAT1CA1
SCHEMBL28643207 0.80 CA12 (0.33) CA12CA14ZDHHC7DGAT1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167222-A1 PROCESS FOR PREPARING OLEFIN-ACRYLATE BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-01 US disclosed
US-9242010-B2 Living copolymer-protein/peptide hybrids for biomedical applications RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2016-01-26 US disclosed
US-8192843-B2 Polymers and polymer coatings CORNELL RESEARCH FOUNDATION, INC. (US) 2012-06-05 US disclosed
US-20120059173-A1 DENDRITIC MOLECULES THE UNIVERSITY OF QUEENSLAND (AU) 2012-03-08 US disclosed
US-20110262991-A1 Living Copolymer-Protein/Peptide Hybrids for Biomedical Applications THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK 2011-10-27 US disclosed
US-20110177343-A1 POLYMERS AND POLYMER COATINGS CORNELL RESEARCH FOUNDATION, INC. (US) 2011-07-21 US disclosed
US-7887790-B2 Polymers and polymer coatings CORNELL RESEARCH FOUNDATION, INC. (US) 2011-02-15 US disclosed
US-20070053867-A1 Polymers and polymer coatings NAVY, SECRETARY OF THE, UNITED STATES OF AMERICA 2007-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120059173-A1 DENDRITIC MOLECULES CD40LG, CD40, TLR3 CA12 1535/4885CA14 2214/4885ZDHHC7 1707/4885
US-20070053867-A1 Polymers and polymer coatings PARG, PUF60, PFAS CA12 158/4885CA14 166/4885ZDHHC7 856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.