Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10383476 | 0.86 | MAPT (0.50) | MAPTKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL10544656 | 0.86 | GAA (0.50) | MAPTBRD4GAA | |
| SCHEMBL10550801 | 0.82 | MAPT (0.41) | MAPTKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL10760165 | 0.80 | ALDH1A1 (0.39) | MAPTKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL8162051 | 0.80 | MAPT (0.53) | MAPTKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL19034718 | 0.80 | FBP1 (0.48) | MAPTKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL2994281 | 0.79 | KDM4E (0.47) | MAPTKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL10819030 | 0.79 | ALDH1A1 (0.47) | MAPTKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL10565947 | 0.79 | ALDH1A1 (0.47) | MAPTKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL10759004 | 0.79 | ALDH1A1 (0.40) | MAPTKDM4ENPC1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083975-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-19 | — | — | EP | claimed |
| EP-0083975-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-20 | — | — | EP | claimed |
| US-4810282-A | 3-ORTHO-(ISOXAZOLYL,ISOTHIAZOLYL, PYRAZOLYL,THIADIAZOLYL, OXADIAZOLYL AND TRIAZOLYL BENZENESULFONUREYLENE-1,2,4-TRIAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0083975-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |
| US-4695311-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-22 | — | — | US | disclosed |
| US-4606755-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-08-19 | — | — | US | disclosed |
| US-4511392-A | N--/PYRIMIDIN-2-YLAMINOCARBENYL/-HETERO-SUBSTITUETED BENZENSESULFO | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0083975-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-20 | — | — | EP | disclosed |