SCHEMBL10545641

SCHEMBL10545641

CCOC(C)N1CC(C)OC1=O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 18/20 0.38
CTSV O60911 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
CTSC P53634 1/20 0.31
CTSF Q9UBX1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8865845 0.87 GRM2 (0.34) GRM2
SCHEMBL10546403 0.84 SMN1; SMN2 (0.40) GRM2
SCHEMBL10545924 0.82 HTR2B (0.35) GRM2CTSVCTSLCTSBCTSS
SCHEMBL8867264 0.81 GRM2 (0.36) GRM2
SCHEMBL10548107 0.79 GRM2 (0.36) GRM2
SCHEMBL13330256 0.77 TSHR (0.38) GRM2
SCHEMBL10308830 0.76 HTR2B (0.38) GRM2
SCHEMBL13765689 0.75 GRM2 (0.36) GRM2
SCHEMBL6551798 0.73 GRM2 (0.34) GRM2
SCHEMBL23875181 0.71 PIK3CD (0.46) CTSVCTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4831153-A PYROLYZING (N-(1-HYDROXYALKYL) OR N-(1-HYDROCARBYLOXYALKYL))-2-OXAZOLIDINONE THE DOW CHEMICAL COMPANY (US) 1989-05-16 US disclosed