SCHEMBL6551798

SCHEMBL6551798

CC1CN(C(C)O)C(=O)O1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 14/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.32
CA1 P00915 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10308830 0.83 HTR2B (0.38) GRM2SMN1; SMN2MAPTCA1CA9
SCHEMBL13330256 0.77 TSHR (0.38) GRM2CA1CA9
SCHEMBL8867264 0.77 GRM2 (0.36) GRM2SMN1; SMN2
SCHEMBL10548107 0.76 GRM2 (0.36) GRM2SMN1; SMN2
SCHEMBL10547493 0.76 HTR2B (0.37) GRM2
SCHEMBL13765689 0.74 GRM2 (0.36) GRM2SMN1; SMN2CA1CA9
SCHEMBL10550222 0.73 GRM2 (0.39) GRM2
SCHEMBL10545641 0.73 GRM2 (0.38) GRM2
SCHEMBL21442758 0.72 CA1 (0.39) GRM2SMN1; SMN2MAPTCA1CA9
SCHEMBL20181103 0.72 CA1 (0.39) GRM2SMN1; SMN2MAPTCA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885941-B1 Ink jet inks containing oxazolidinones XEROX CORP (US) 2004-02-18 EP claimed
US-5882389-A WATER, COLOR AND OXAZOLIDINONE XEROX CORPORATION (US) 1999-03-16 US claimed
EP-0885941-B1 Ink jet inks containing oxazolidinones XEROX CORP (US) 2004-02-18 EP disclosed
US-6225370-B1 FOR USE WITH INK JET PRINTERS LEXMARK INTERNATIONAL, INC. 2001-05-01 US disclosed
US-5882389-A WATER, COLOR AND OXAZOLIDINONE XEROX CORPORATION (US) 1999-03-16 US disclosed
EP-0885941-A1 Ink jet inks containing oxazolidinones Xerox Corporation (US) 1998-12-23 EP disclosed
US-4831153-A PYROLYZING (N-(1-HYDROXYALKYL) OR N-(1-HYDROCARBYLOXYALKYL))-2-OXAZOLIDINONE THE DOW CHEMICAL COMPANY (US) 1989-05-16 US disclosed