Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 12/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865845 | 0.91 | GRM2 (0.34) | SMN1; SMN2HPGDALDH1A1GRM2 | |
| SCHEMBL10545641 | 0.84 | GRM2 (0.38) | GRM2 | |
| SCHEMBL10549013 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDALDH1A1GRM2 | |
| SCHEMBL8867264 | 0.76 | GRM2 (0.36) | SMN1; SMN2GRM2 | |
| SCHEMBL10548107 | 0.74 | GRM2 (0.36) | SMN1; SMN2GRM2 | |
| SCHEMBL10550159 | 0.73 | NAAA (0.41) | SMN1; SMN2HPGDALDH1A1THRATHRB | |
| SCHEMBL13330256 | 0.73 | TSHR (0.38) | GRM2 | |
| SCHEMBL10308830 | 0.71 | HTR2B (0.38) | SMN1; SMN2GRM2 | |
| SCHEMBL13765689 | 0.71 | GRM2 (0.36) | SMN1; SMN2GRM2 | |
| SCHEMBL6551798 | 0.69 | GRM2 (0.34) | SMN1; SMN2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831153-A | PYROLYZING (N-(1-HYDROXYALKYL) OR N-(1-HYDROCARBYLOXYALKYL))-2-OXAZOLIDINONE | THE DOW CHEMICAL COMPANY (US) | 1989-05-16 | — | — | US | disclosed |