Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714941 | 0.92 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL6089752 | 0.89 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL10544006 | 0.88 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL10547968 | 0.87 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL7008540 | 0.86 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2 | |
| SCHEMBL10421916 | 0.83 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2 | |
| SCHEMBL7710959 | 0.83 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2 | |
| SCHEMBL7714687 | 0.81 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2 | |
| SCHEMBL10422016 | 0.81 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2 | |
| SCHEMBL10546763 | 0.81 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839369-A | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | RORER PHARMACEUTICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0200101-A2 | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive aliments | USV PHARMACEUTICAL CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |