Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643206 | 1.00 | TDP1 (0.75) | TDP1ALDH1A1CTSBCYP3A4ALOX15 | |
| SCHEMBL8722948 | 0.88 | TDP1 (0.61) | TDP1ALDH1A1CTSBCYP3A4ALOX15 | |
| SCHEMBL57166 | 0.87 | TDP1 (1.00) | TDP1ALDH1A1CTSBCYP3A4ALOX15 | |
| SCHEMBL29475175 | 0.87 | TDP1 (1.00) | TDP1ALDH1A1CTSBCYP3A4ALOX15 | |
| SCHEMBL17035156 | 0.85 | TDP1 (0.53) | TDP1ALDH1A1CTSBCYP3A4ALOX15 | |
| SCHEMBL28093598 | 0.84 | TDP1 (0.95) | TDP1ALDH1A1CTSBCYP3A4ALOX15 | |
| SCHEMBL27009722 | 0.83 | S100A4 (0.53) | TDP1ALDH1A1CTSBCYP3A4ALOX15 | |
| SCHEMBL15822880 | 0.81 | ALDH1A1 (0.51) | TDP1ALDH1A1CTSBCYP3A4ALOX15 | |
| Methyl Alcohol SCHEMBL28304524 | 0.80 | TDP1 (0.86) | TDP1ALDH1A1CTSBCYP3A4ALOX15 | |
| SCHEMBL9669809 | 0.80 | CTSB (0.58) | TDP1ALDH1A1CTSBCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113150273-B | Preparation method of nitrogen-containing polymer | 中国科学院福建物质结构研究所 | 2024-01-23 | — | — | CN | claimed |
| CN-113150273-A | Preparation method of nitrogen-containing polymer | 中国科学院福建物质结构研究所 | 2021-07-23 | — | — | CN | claimed |
| CN-110511230-A | Compound and the preparation method and application thereof, organic electrochromic device | UNIV PEKING SHENZHEN GRADUATE SCHOOL | 2019-11-29 | — | — | CN | claimed |
| CN-102924330-A | Method for large-scale preparation of 5-amino-1-naphthyl nitrile | UNIV EAST CHINA SCIENCE & TECH | 2013-02-13 | — | — | CN | claimed |
| JP-8151353-A | — | — | None | — | — | JP | disclosed |
| US-12448391-B2 | Bicyclic derivatives for treating endoparasites | ELANCO TIERGESUNDHEIT AG (CH) | 2025-10-21 | — | — | US | disclosed |
| WO-2025134136-A1 | A COMPOUND, A PROBE, AND METHODS THEREOF | L’OREAL (FR) | 2025-06-26 | — | — | WO | disclosed |
| EP-3617213-B1 | THIENO[3,2-D]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASES | HANMI PHARMACEUTICAL CO LTD (KR) | 2025-02-19 | — | — | EP | disclosed |
| CN-114206860-B | Bicyclic derivatives for the treatment of endoparasites | 礼蓝动物保健有限公司 | 2025-02-18 | — | — | CN | disclosed |
| EP-3897842-B1 | BICYCLIC DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2025-01-29 | — | — | EP | disclosed |
| US-20240360116-A1 | BICYCLIC DERIVATIVES | ELANCO TIERGESUNDHEIT AG (SZ) | 2024-10-31 | — | — | US | disclosed |
| CN-116212873-B | Alumina-supported copper heterogeneous catalyst with molecular imprinting function and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2024-10-29 | — | — | CN | disclosed |
| US-6075133-A | INCREASED ACID STABILITY AND ENHANCED BACTERICIDAL ACTIVITY | ABBOTT LABORATORIES (US) | 2000-06-13 | — | — | US | disclosed |
| US-6028181-A | 6-0-Substituted antibacterial erythromycin ketolides and methods of making | ABBOTT LABORATORIES (US) | 2000-02-22 | — | — | US | disclosed |
| CN-1237183-A | 6-0-substituted ketolides with antibacterial activity | ABBOTT CO (US) | 1999-12-01 | — | — | CN | disclosed |
| EP-0929563-A1 | 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY | Abbott Laboratories (US) | 1999-07-21 | — | — | EP | disclosed |
| US-5866549-A | MACROLIDE ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1999-02-02 | — | — | US | disclosed |
| WO-1998009978-A1 | 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY | ABBOTT LABORATORIES (US) | 1998-03-12 | — | — | WO | disclosed |
| JP-H08151353-A | PRODUCTION OF 1-AMINO-5-BROMONAPHTHALENE | MITSUI TOATSU CHEM INC | 1996-06-11 | — | — | JP | disclosed |
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12448391-B2 | Bicyclic derivatives for treating endoparasites | TBXA2R, PIGS, CYCS | TDP1 4342/4885ALDH1A1 1017/4885CTSB 788/4885 |
| US-20240360116-A1 | BICYCLIC DERIVATIVES | FABP3, CYCS, TNNI3 | TDP1 4813/4885ALDH1A1 611/4885CTSB 1685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.