Folpet

Folpet

SCHEMBL10548352

O=C1c2ccccc2C(=O)N1SC(Cl)(Cl)Cl.S=C([S-])NCCNC(=S)[S-].[Zn+2]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.38
CA9 Q16790 6/20 0.38
CA1 P00915 6/20 0.38
CA2 P00918 6/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
ALOX15 P16050 3/20 0.38
THRB P10828 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
RECQL P46063 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ASAH1 Q13510 2/20 0.32
PKM P14618 2/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 2/20 0.31
PLIN1 O60240 1/20 0.31
PLIN5 Q00G26 1/20 0.31
ABHD5 Q8WTS1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Folpet SCHEMBL9315225 0.87 CA12 (0.32) CA12CA9CA1CA2
Folpet SCHEMBL11225944 0.82 ALDH1A1 (0.36) ALDH1A1HPGDALOX15HSD17B10CYP3A4
Folpet SCHEMBL29539926 0.79 ALDH1A1 (0.43) CA12CA9ALDH1A1HPGDALOX15
Folpet SCHEMBL19853 0.79 ALDH1A1 (0.43) CA12CA9ALDH1A1HPGDALOX15
Folpet SCHEMBL15757128 0.79 ALDH1A1 (0.43) CA12CA9ALDH1A1HPGDALOX15
Folpet SCHEMBL9719554 0.76 ALDH1A1 (0.39) CA12CA9ALDH1A1HPGDALOX15
Zinc Ion SCHEMBL11218497 0.76 ALDH1A1 (0.34) ALDH1A1HPGDALOX15HSD17B10CYP3A4
Captan SCHEMBL11365785 0.73 ALDH1A1 (0.62) ALDH1A1HPGDALOX15THRBHSD17B10
Folpet SCHEMBL7750868 0.73 ALDH1A1 (0.42) CA12CA9ALDH1A1HPGDALOX15
Anthraquinone SCHEMBL8501112 0.73 THRB (0.52) CA12CA9CA1CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109042699-A Synergistic bactericidal composition comprising folpet and zineb 广东广康生化科技股份有限公司 2018-12-21 CN disclosed
US-4812162-A PLANT GROWTH REGULATORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-03-14 US disclosed
US-4743602-A AND CORRESPONDING FURANS, PYRROLES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-10 US disclosed