Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.54 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10547665 | 0.85 | LTA4H (0.54) | LTA4HNQO1FFAR1TSHRHSD17B10 | |
| SCHEMBL10549588 | 0.84 | SMN1; SMN2 (0.56) | LTA4HMTNR1BALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10549842 | 0.84 | FFAR1 (0.47) | FFAR1MTNR1BTSHRHSD17B10ALDH1A1 | |
| SCHEMBL9292349 | 0.84 | TSHR (0.47) | LTA4HFFAR1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL10546949 | 0.81 | FDFT1 (0.43) | LTA4HFFAR1MTNR1BALDH1A1KDM4E | |
| SCHEMBL10547235 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2HTTCETP | |
| SCHEMBL10551659 | 0.81 | ALDH1A1 (0.39) | FFAR1MTNR1BTSHRHSD17B10ALDH1A1 | |
| SCHEMBL924115 | 0.80 | LTA4H (0.59) | LTA4HNQO1FFAR1TSHRTP53 | |
| SCHEMBL5248003 | 0.78 | NQO1 (0.58) | LTA4HNQO1TSHRALDH1A1KDM4E | |
| SCHEMBL11745385 | 0.78 | LTA4H (0.73) | LTA4HNQO1TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814340-A | 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |