Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 13/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 13/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.47 |
| ▸ | PDE4A | P27815 | 4/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287604 | 0.80 | PDE3B (0.70) | PDE3BPDE3APDE4BPDE4APDE4C | |
| SCHEMBL3412583 | 0.75 | SMN1; SMN2 (0.47) | PDE3BPDE3APDE4BPDE4APDE4C | |
| SCHEMBL10551396 | 0.73 | SMN1; SMN2 (0.46) | PDE3BPDE3APDE4BPDE4APDE4C | |
| SCHEMBL11568322 | 0.71 | SMN1; SMN2 (0.59) | PDE3BPDE3APDE4BPDE4APDE4C | |
| SCHEMBL7318837 | 0.70 | PDE3B (0.68) | PDE3BPDE3APDE4BPDE4APDE4C | |
| SCHEMBL20204020 | 0.67 | MAPT (0.45) | PDE3BPDE3APDE4BPDE4APDE4C | |
| SCHEMBL15788581 | 0.65 | POLB (0.53) | POLB | |
| SCHEMBL7286021 | 0.65 | PDE3B (0.70) | PDE3BPDE3APDE4BPDE4APDE4C | |
| SCHEMBL31049765 | 0.64 | KDM4E (0.52) | LMNACYP1A2TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL10353452 | 0.64 | SMN1; SMN2 (0.81) | PDE3BPDE3APDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847251-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-11 | — | — | US | disclosed |