Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970712 | 0.85 | CYP3A4 (0.38) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL10924650 | 0.83 | CYP3A4 (0.33) | TSHRCYP3A4MAPTCACNA1BAPBA1 | |
| SCHEMBL9167074 | 0.82 | TSHR (0.36) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL25936073 | 0.82 | TSHR (0.32) | TSHRCYP3A4MAPTCACNA1BAPBA1 | |
| SCHEMBL10561972 | 0.80 | TSHR (0.30) | TSHR | |
| SCHEMBL2255510 | 0.80 | SOAT1 (0.39) | TSHRMAPT | |
| SCHEMBL6418608 | 0.79 | TSHR (0.46) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL27550038 | 0.77 | HCAR2 (0.33) | TSHRTDP1 | |
| SCHEMBL14642009 | 0.76 | NPSR1 (0.35) | TSHR | |
| SCHEMBL27898356 | 0.76 | TSHR (0.43) | TSHRCYP3A4TDP1MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1277819-C | Process for producing azetidinone compounds | TAKASAGO PERFUMERY CO LTD (JP) | 2006-10-04 | — | — | CN | disclosed |
| CN-1610663-A | Process for producing azetidinone compounds | TAKASAGO PERFUMERY CO LTD (JP) | 2005-04-27 | — | — | CN | disclosed |
| US-4841043-A | Stereoselective synthesis of 1-β-alkyl carbapenem antibiotic intermediates | BRISTOL-MYERS COMPANY (US) | 1989-06-20 | — | — | US | disclosed |
| US-4841042-A | Process for the preparation of carbapenem intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| EP-0195963-A1 | Process for the preparation of carbapenem intermediates | BAYER AG (DE) | 1986-10-01 | — | — | EP | disclosed |