Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27898356 | 0.87 | TSHR (0.43) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL28064773 | 0.82 | TSHR (0.46) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL11667699 | 0.81 | TSHR (0.39) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL468460 | 0.80 | TSHR (0.44) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL177943 | 0.80 | CYP3A4 (0.48) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL10548645 | 0.79 | TSHR (0.38) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL1651451 | 0.79 | CYP3A4 (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL11123251 | 0.78 | TSHR (0.66) | TSHRHPGD | |
| SCHEMBL7512684 | 0.78 | CYP3A4 (0.46) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL17809616 | 0.77 | MAPT (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428166-A | Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs | NORTH CAROLINA STATE UNIVERSITY (US) | 1995-06-27 | — | — | US | claimed |
| WO-2022138891-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE | 中外製薬株式会社 | 2022-06-30 | — | — | WO | disclosed |
| EP-0963988-B1 | Intermediates for making camptothecin and camptothecin analogs | UNIV NORTH CAROLINA STATE (US) | 2005-04-27 | — | — | EP | disclosed |
| EP-1142894-B1 | Volatile precursors for deposition of metals and metal-containing films | AIR PROD & CHEM (US) | 2005-01-12 | — | — | EP | disclosed |
| US-6818783-B2 | HOMOLOGOUS EIGHT MEMBERED RING COMPOUNDS HAVING A METAL, SUCH AS COPPER, REVERSIBLY BOUND IN THE RING AND CONTAINING CARBON, NITROGEN, SILICON AND/OR OTHER METALS. | AIR PRODUCTS AND CHEMICALS, INC. | 2004-11-16 | — | — | US | disclosed |
| US-20040215030-A1 | Precursors for metal containing films | VERSUM MATERIALS US, LLC | 2004-10-28 | — | — | US | disclosed |
| EP-1471568-A1 | Precursors for metal containing films | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2004-10-27 | — | — | EP | disclosed |
| US-20030135061-A1 | Volatile precursors for deposition of metals and metal-containing films | VERSUM MATERIALS US, LLC | 2003-07-17 | — | — | US | disclosed |
| US-20020013487-A1 | Volatile precursors for deposition of metals and metal-containing films | VERSUM MATERIALS US, LLC | 2002-01-31 | — | — | US | disclosed |
| EP-1142894-A2 | Volatile precursors for deposition of metals and metal-containing films | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5212317-A | Methods and intermediates for the assymmetric synthesis of camptothecin and camptothecin analogs | NORTH CAROLINA STATE UNIVERSITY (US) | 1993-05-18 | — | — | US | disclosed |
| US-5200524-A | Camptothecin intermediates and method of making same | NORTH CAROLINA STATE UNIVERSITY (US) | 1993-04-06 | — | — | US | disclosed |
| US-5191082-A | Camptothecin intermediate and method of making camptothecin intermediates | NORTH CAROLINA STATE UNIVERSITY (US) | 1993-03-02 | — | — | US | disclosed |
| US-5162532-A | INTERMEDIATES AND METHOD OF MAKING CAMPTOTHECIN AND CAMPTOTHECIN ANALOGS | NORTH CAROLINA STATE UNIVERSITY (US) | 1992-11-10 | — | — | US | disclosed |
| WO-1992011263-A1 | METHOD OF MAKING CAMPTOTHECIN AND CAMPTOTHECIN ANALOGS | NORTH CAROLINA STATE UNIVERSITY (US) | 1992-07-09 | — | — | WO | disclosed |
| EP-0299727-B1 | THERAPEUTIC AGENTS | Pfizer Limited (GB) | 1991-11-13 | — | — | EP | disclosed |
| US-4992447-A | Asthma | PFIZER INC. (US) | 1991-02-12 | — | — | US | disclosed |
| US-4853392-A | Fused 1,4-dihydropyridines as antiallergy and antiinflammatory agents | PFIZER INC. (US) | 1989-08-01 | — | — | US | disclosed |
| EP-0299727-A1 | Therapeutic agents | Pfizer Limited (GB) | 1989-01-18 | — | — | EP | disclosed |
| US-4480120-A | Process for the preparation of alkyl-2-alkoxyimino-3-oxo-4-chlorobutyrates | EASTMAN KODAK COMPANY (US) | 1984-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013487-A1 | Volatile precursors for deposition of metals and metal-containing films | SOD1, C1R, C5 | TSHR 3274/4885CYP3A4 1078/4885TDP1 4468/4885 |
| US-20030135061-A1 | Volatile precursors for deposition of metals and metal-containing films | SOD1, C1R, C5 | TSHR 3302/4885CYP3A4 1185/4885TDP1 4378/4885 |
| US-20040215030-A1 | Precursors for metal containing films | TBL3, TBL2, TNNI3 | TSHR 2197/4885CYP3A4 1453/4885TDP1 3119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.