Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398650 | 0.88 | ACHE (0.60) | FFAR1ACHEHPGDCYP3A4CYP2C19 | |
| SCHEMBL11399936 | 0.88 | ACHE (0.60) | FFAR1ACHEHPGDCYP3A4CYP2C19 | |
| SCHEMBL4445084 | 0.82 | TAAR1 (0.52) | FFAR1ACHEHPGDCYP3A4CYP2C19 | |
| SCHEMBL6178878 | 0.82 | ALDH1A1 (0.50) | FFAR1ACHEHPGDCYP3A4CYP2C19 | |
| SCHEMBL18980600 | 0.82 | ALDH1A1 (0.50) | FFAR1ACHEHPGDCYP3A4CYP2C19 | |
| SCHEMBL11154821 | 0.81 | FFAR1 (0.53) | FFAR1ACHEHPGDCYP3A4CYP2C19 | |
| SCHEMBL11673964 | 0.80 | FFAR1 (0.51) | FFAR1HPGDCYP3A4CYP2C19RAB9A | |
| SCHEMBL237091 | 0.79 | FFAR1 (0.70) | FFAR1HPGDCYP3A4CYP2C19RAB9A | |
| SCHEMBL1149768 | 0.79 | FFAR1 (0.70) | FFAR1HPGDCYP3A4CYP2C19RAB9A | |
| SCHEMBL237090 | 0.79 | FFAR1 (0.70) | FFAR1HPGDCYP3A4CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826864-A | Substituted imidazole derivatives useful as antihypertensive or antithromtic agent or divretic | FARMOS GROUP LTD. (FI) | 1989-05-02 | — | — | US | disclosed |
| US-4639464-A | Antihypertensive substituted imidazole derivatives | FARMOS GROUP, LTD. (FI) | 1987-01-27 | — | — | US | disclosed |
| EP-0072615-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1985-12-27 | — | — | EP | disclosed |
| US-4544664-A | Antihypertensive substituted imidazole derivatives | FARMOS GROUP, LTD. (FI) | 1985-10-01 | — | — | US | disclosed |