SCHEMBL10549355

SCHEMBL10549355

CCC(C)(CCCc1cccc(Oc2ccccc2)c1)c1ccc(OC(F)(F)C(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 18/20 0.47
FDFT1 P37268 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10544536 0.89 FDFT1 (0.46) FDFT1
SCHEMBL10544623 0.88 CETP (0.46) CETPFDFT1
SCHEMBL10545673 0.87 FDFT1 (0.42) CETPFDFT1
SCHEMBL10547464 0.87 FDFT1 (0.47) CETPFDFT1
SCHEMBL9558003 0.85 FDFT1 (0.46) FDFT1
SCHEMBL9558187 0.85 KDM4E (0.50) FDFT1
SCHEMBL10547498 0.84 FDFT1 (0.49) FDFT1
SCHEMBL10543647 0.84 CETP (0.42) CETPFDFT1
SCHEMBL10547619 0.84 LTA4H (0.49) CETPFDFT1
SCHEMBL10548418 0.83 FDFT1 (0.43) FDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4814340-A 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity MITSUI TOATSU CHEMICALS, INC. (JP) 1989-03-21 US disclosed
US-4661501-A Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity MITSUI TOATSU CHEMICALS, INC. (JP) 1987-04-28 US disclosed