Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 6/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10544536 | 0.93 | FDFT1 (0.46) | FDFT1NPC1POLBCYP2C9RAB9A | |
| SCHEMBL9558003 | 0.91 | FDFT1 (0.46) | FDFT1NPC1POLBCYP2C9RAB9A | |
| SCHEMBL10547498 | 0.90 | FDFT1 (0.49) | FDFT1NPC1POLBCYP2C9RAB9A | |
| SCHEMBL10543647 | 0.90 | CETP (0.42) | FDFT1CETPMAPK14NPC1POLB | |
| SCHEMBL10548418 | 0.89 | FDFT1 (0.43) | FDFT1NPC1POLBCYP2C9RAB9A | |
| SCHEMBL10546909 | 0.88 | FDFT1 (0.42) | FDFT1NPC1POLBCYP2C9RAB9A | |
| SCHEMBL9558187 | 0.88 | KDM4E (0.50) | FDFT1NPC1POLBCYP2C9RAB9A | |
| SCHEMBL9559051 | 0.88 | ALDH1A1 (0.44) | FDFT1NPC1POLBCYP2C9RAB9A | |
| SCHEMBL10547619 | 0.87 | LTA4H (0.49) | FDFT1CETPNPC1POLBCYP2C9 | |
| SCHEMBL10549355 | 0.87 | CETP (0.47) | FDFT1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814340-A | 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |