Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211550 | 0.81 | ALDH1A1 (0.40) | RAB9AKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL19551413 | 0.77 | KLK7 (0.54) | RAB9AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11171293 | 0.75 | NPSR1 (0.43) | RAB9AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6285272 | 0.74 | CNR2 (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2FFAR1 | |
| SCHEMBL1521950 | 0.73 | CA1 (0.50) | RAB9AMEN1KMT2AALDH1A1FFAR1 | |
| SCHEMBL9626243 | 0.72 | SMN1; SMN2 (0.44) | RAB9AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7216770 | 0.72 | FFAR1 (0.53) | KMT2AALDH1A1HTTFFAR1CNR2 | |
| SCHEMBL5484162 | 0.72 | ALDH1A1 (0.49) | RAB9AMEN1KMT2AALDH1A1FFAR1 | |
| SCHEMBL1354 | 0.71 | CA1 (0.46) | RAB9AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9698724 | 0.71 | KLK7 (0.47) | RAB9AMEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839352-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-06-13 | — | — | US | disclosed |