Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285272 | 0.88 | CNR2 (0.50) | FFAR1KMT2ALMNACNR1CNR2 | |
| SCHEMBL5484162 | 0.88 | ALDH1A1 (0.49) | FFAR1KMT2ALMNAMAPK1NPSR1 | |
| SCHEMBL5183992 | 0.87 | ATM (0.55) | FFAR1KMT2AKLK7GAAPOLB | |
| SCHEMBL1521950 | 0.87 | CA1 (0.50) | FFAR1KMT2ACNR2PPARGPPARA | |
| SCHEMBL11650986 | 0.86 | FFAR1 (0.47) | FFAR1KMT2ALMNAMAPK1HTT | |
| SCHEMBL7278760 | 0.83 | GAA (0.53) | KMT2AMAPK1HTTGAAATM | |
| SCHEMBL4438089 | 0.83 | GAA (0.53) | KMT2AMAPK1HTTGAAATM | |
| SCHEMBL5050204 | 0.77 | IDO1 (0.38) | KMT2ALMNACNR2HTTALDH1A1 | |
| SCHEMBL8819465 | 0.77 | TDP1 (0.45) | KMT2ALMNAHTTNPSR1HPGD | |
| SCHEMBL9626243 | 0.76 | SMN1; SMN2 (0.44) | KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617342-B1 | Treating hyperglycemia associated with non- insulin dependant diabetes and for treating hyperlipidemia. | ELI LILLY AND COMPANY | 2003-09-09 | — | — | US | disclosed |
| US-6617343-B1 | Treating non-insulin-dependent diabetes mellitus | ELI LILLY AND COMPANY | 2003-09-09 | — | — | US | disclosed |
| WO-1997042155-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-11-13 | — | — | WO | disclosed |
| EP-0729468-A1 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0729468-A4 | NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1996-07-12 | — | — | EP | disclosed |
| EP-0485103-A2 | Process for cleavage of esters during the production of cephalosporins | ELI LILLY AND COMPANY (US) | 1992-05-13 | — | — | EP | disclosed |