Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474938 | 0.80 | GABRR1 (0.32) | TBXA2RTBXAS1GABRR1GABRR2BLM | |
| SCHEMBL4389137 | 0.80 | GABRR1 (0.34) | TBXA2RGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL1469403 | 0.77 | TSHR (0.38) | TBXAS1GABRR1GABRR2BLMGABRR3 | |
| Acrylic Acid SCHEMBL10479959 | 0.73 | LMNA (0.31) | LMNA | |
| SCHEMBL442394 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL9825991 | 0.71 | GABRR1 (0.33) | TBXAS1GABRR1GABRR2BLMGABRR3 | |
| SCHEMBL12074895 | 0.71 | TSHR (0.43) | TBXA2RBLMLMNATSHRAPEX1 | |
| SCHEMBL10586703 | 0.71 | TSHR (0.43) | TBXA2RBLMLMNATSHRAPEX1 | |
| Acetic Acid SCHEMBL10480045 | 0.70 | ALDH1A1 (0.37) | — | |
| SCHEMBL20598722 | 0.70 | PPARA (0.38) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824858-A | THROMBOXANE A2 ANTAGONIST | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-04-25 | — | — | US | disclosed |