SCHEMBL10550222

SCHEMBL10550222

CCCC1CN(C(C)O)C(=O)O1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 16/20 0.39
HTR2B P41595 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10547493 0.86 HTR2B (0.37) GRM2HTR2B
SCHEMBL6551798 0.73 GRM2 (0.34) GRM2
SCHEMBL11886636 0.73 GRM2 (0.44) GRM2
SCHEMBL10249502 0.73 GRM2 (0.44) GRM2
SCHEMBL13647701 0.72 HTR2B (0.48) GRM2HTR2B
SCHEMBL14116945 0.72 HTR2B (0.48) GRM2HTR2B
SCHEMBL9744077 0.71 HTR2B (0.45) GRM2HTR2B
SCHEMBL6214722 0.70 HTR2B (0.47) HTR2B
SCHEMBL6212651 0.70 HTR2B (0.47) HTR2B
SCHEMBL6212644 0.70 HTR2B (0.47) HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4831153-A PYROLYZING (N-(1-HYDROXYALKYL) OR N-(1-HYDROCARBYLOXYALKYL))-2-OXAZOLIDINONE THE DOW CHEMICAL COMPANY (US) 1989-05-16 US disclosed