Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CALML3 | P27482 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212644 | 1.00 | HTR2B (0.47) | HTR2BMAOAMAOBMAPTCALML3 | |
| SCHEMBL6212651 | 1.00 | HTR2B (0.47) | HTR2BMAOAMAOBMAPTCALML3 | |
| SCHEMBL10370432 | 0.92 | HTR2B (0.42) | HTR2BMAOAMAOBMAPTCALML3 | |
| SCHEMBL14116945 | 0.83 | HTR2B (0.48) | HTR2BMAOAMAPT | |
| SCHEMBL13647701 | 0.83 | HTR2B (0.48) | HTR2BMAOAMAPT | |
| SCHEMBL20989997 | 0.81 | HTR2B (0.47) | HTR2BMAOAMAPT | |
| SCHEMBL7678549 | 0.81 | HTR2B (0.47) | HTR2BMAOAMAPT | |
| SCHEMBL22849920 | 0.81 | HTR2B (0.47) | HTR2BMAOAMAPT | |
| SCHEMBL14168076 | 0.81 | HTR2B (0.47) | HTR2BMAOAMAPT | |
| SCHEMBL25822393 | 0.81 | HTR2B (0.47) | HTR2BMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339006-B1 | PROCESS FOR PREPARING S-METOPROLOL AND INTERMEDIATES THEREFOR | Astra Pharmaceutical Production AB (SE) | 1992-07-08 | — | — | EP | claimed |
| US-5034535-A | Multistage reaction with chloroformate ester and isopropylamino-1,2-propanediol for cyclization, sulfonation and etherification | ASTRA PHARMACEUTICAL PRODUCTION AKTIEBOLAG (SE) | 1991-07-23 | — | — | US | claimed |
| EP-0339006-A1 | Process for preparing S-metoprolol and intermediates therefor | Astra Pharmaceutical Production AB (SE) | 1989-10-25 | — | — | EP | claimed |
| US-11858946-B2 | Small molecules active against gram-negative bacteria | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-01-02 | — | — | US | disclosed |
| US-10995097-B2 | Small molecules active against gram-negative bacteria | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-05-04 | — | — | US | disclosed |
| US-20190135821-A1 | SMALL MOLECULES ACTIVE AGAINST GRAM-NEGATIVE BACTERIA | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2019-05-09 | — | — | US | disclosed |
| CN-104761458-A | S-metoprolol succinate crystal form and preparation method thereof | ZHONGSHUAI PHARMACEUTICAL SCI & TECH INC CO LTD | 2015-07-08 | — | — | CN | disclosed |
| US-7390825-B1 | Process for the preparation of oxazolidinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-06-24 | — | — | US | disclosed |
| US-7390825-B1 | Process for the preparation of oxazolidinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-06-24 | — | — | US | disclosed |
| US-20080146458-A1 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-06-19 | — | — | US | disclosed |
| US-20080146458-A1 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-06-19 | — | — | US | disclosed |
| US-5034535-A | Multistage reaction with chloroformate ester and isopropylamino-1,2-propanediol for cyclization, sulfonation and etherification | ASTRA PHARMACEUTICAL PRODUCTION AKTIEBOLAG (SE) | 1991-07-23 | — | — | US | disclosed |
| US-5034535-A | Multistage reaction with chloroformate ester and isopropylamino-1,2-propanediol for cyclization, sulfonation and etherification | ASTRA PHARMACEUTICAL PRODUCTION AKTIEBOLAG (SE) | 1991-07-23 | — | — | US | disclosed |
| US-4933290-A | REACTING WITH AN ESTER, ACID, OR ANHYDRIDE IN THE PRESENCE OF A LIPASE IMMOBILIZED ON A POROUS CARRIER | MONTEDISON S.P.A. (IT) | 1990-06-12 | — | — | US | disclosed |
| EP-0339006-A1 | Process for preparing S-metoprolol and intermediates therefor | Astra Pharmaceutical Production AB (SE) | 1989-10-25 | — | — | EP | disclosed |
| EP-0339006-A1 | Process for preparing S-metoprolol and intermediates therefor | Astra Pharmaceutical Production AB (SE) | 1989-10-25 | — | — | EP | disclosed |
| EP-0101076-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE OXAZOLIDINONE DERIVATIVE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-01-04 | — | — | EP | disclosed |
| EP-0274277-A2 | A process for the enzymatic separation of the optical isomers of racemic oxazolidinonic derivatives | Montedison S.p.A. (IT) | 1988-07-13 | — | — | EP | disclosed |
| US-4588694-A | HYDROLYSIS, MICROORGANISM OR ENZYME, RACEMIC 3-ALKYL-5-ACYLOXYMETHYLOXAZOLIDIN-2-ONE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-05-13 | — | — | US | disclosed |
| EP-0101076-A2 | Process for production of optically active oxazolidinone derivative | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10995097-B2 | Small molecules active against gram-negative bacteria | PGLS, MRPL21, CLPP | HTR2B 3574/4885MAOA 466/4885MAOB 320/4885 |
| US-20080146458-A1 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | OXA1L, OGFOD1, CYP51A1 | HTR2B 2619/4885MAOA 1290/4885MAOB 325/4885 |
| US-11858946-B2 | Small molecules active against gram-negative bacteria | PGLS, MRPL21, CLPP | HTR2B 3877/4885MAOA 701/4885MAOB 503/4885 |
| US-20190135821-A1 | SMALL MOLECULES ACTIVE AGAINST GRAM-NEGATIVE BACTERIA | PGLS, MRPL21, CLPP | HTR2B 3574/4885MAOA 466/4885MAOB 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.