Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G6 | O60733 | 2/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10549390 | 0.91 | GRM2 (0.48) | PLA2G6PLA2G4AGRM2CYP1A2CYP2C9 | |
| SCHEMBL10553588 | 0.90 | GRM2 (0.49) | PLA2G6PLA2G4AGRM2CYP1A2 | |
| SCHEMBL10550091 | 0.88 | GRM2 (0.50) | PLA2G6GRM2CYP1A2 | |
| SCHEMBL10550397 | 0.88 | GRM2 (0.50) | PLA2G6GRM2CYP1A2 | |
| SCHEMBL10553021 | 0.88 | GRM2 (0.50) | PLA2G6GRM2CYP1A2 | |
| SCHEMBL10548384 | 0.86 | GRM2 (0.37) | GRM2KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL6291805 | 0.86 | PLA2G6 (0.41) | PLA2G6PLA2G4AGRM2KMT2AMEN1 | |
| SCHEMBL10555091 | 0.85 | GRM2 (0.39) | GRM2CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL10550344 | 0.85 | CYP3A4 (0.46) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10549682 | 0.85 | SLC6A3 (0.39) | GRM2KMT2AMEN1SMN1; SMN2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818431-A | ELECTROOPTICAL DISPLAY ELEMENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-04-04 | — | — | US | disclosed |
| EP-0117476-B1 | TETRAHYDROPYRANES | MERCK PATENT GmbH (DE) | 1987-09-16 | — | — | EP | disclosed |
| EP-0117476-A1 | Tetrahydropyranes | MERCK PATENT GmbH (DE) | 1984-09-05 | — | — | EP | disclosed |