Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | DRD2 | P14416 | 2/20 | 0.64 |
| ▸ | DRD1 | P21728 | 2/20 | 0.64 |
| ▸ | DRD3 | P35462 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD5 | P21918 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16674495 | 0.87 | POLB (0.62) | MEN1KMT2AGAADRD2DRD1 | |
| SCHEMBL16674505 | 0.87 | KDM4E (0.54) | MEN1KMT2AGAADRD2DRD1 | |
| SCHEMBL1286685 | 0.85 | MAPT (0.81) | MEN1KMT2AGAADRD2DRD1 | |
| SCHEMBL11712503 | 0.85 | DRD2 (0.72) | MEN1KMT2AGAADRD2DRD1 | |
| SCHEMBL11712364 | 0.85 | DRD2 (0.72) | MEN1KMT2AGAADRD2DRD1 | |
| SCHEMBL11801298 | 0.85 | DRD2 (0.72) | MEN1KMT2AGAADRD2DRD1 | |
| SCHEMBL11730898 | 0.85 | DRD2 (0.72) | MEN1KMT2AGAADRD2DRD1 | |
| SCHEMBL8401002 | 0.83 | DRD2 (0.75) | MEN1KMT2AGAADRD2DRD1 | |
| SCHEMBL11365759 | 0.83 | DRD2 (0.75) | MEN1KMT2AGAADRD2DRD1 | |
| SCHEMBL11804646 | 0.83 | DRD2 (0.74) | MEN1KMT2AGAADRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | THE UNITED STATES OF AMERICA AS REPRESENTED BY SECRETARY DEPT OF HEALTH AND HUMAN SERVICE (US) | 2017-05-25 | — | — | US | disclosed |
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | THE UNITED STATES OF AMERICA AS REPRESENTED BY SECRETARY DEPT OF HEALTH AND HUMAN SERVICE (US) | 2017-05-25 | — | — | US | disclosed |
| US-9452973-B2 | Modulators of the relaxin receptor 1 | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2016-09-27 | — | — | US | disclosed |
| US-20150119426-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES | 2015-04-30 | — | — | US | disclosed |
| US-4831051-A | CALCIUM ANTAGONIST; ANTIARRHYTHMIA, HYPOTENSIVE AND CARDIOTONIC AGENTS; VASODILATION | DELANDE S.A. (FR) | 1989-05-16 | — | — | US | disclosed |
| US-4732896-A | ANTAGONIST TO CALCIUM | DELALANDE S.A. (FR) | 1988-03-22 | — | — | US | disclosed |
| US-4536500-A | ANTAGONISTIC ACTIVITY TO CALCIUM | DELALANDE S.A. (FR) | 1985-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119426-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | RXFP1, RXFP2, RXFP3 | MEN1 687/4885KMT2A 4449/4885GAA 3991/4885 |
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | RXFP1, RXFP2, RXFP3 | MEN1 687/4885KMT2A 4449/4885GAA 3991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.