Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10557493 | 0.97 | RAB9A (0.47) | RAB9ALMNACRBNNPC1MAOA | |
| SCHEMBL10552489 | 0.96 | RAB9A (0.46) | RAB9ALMNACRBNALDH1A1MAPT | |
| SCHEMBL10554049 | 0.93 | RAB9A (0.48) | RAB9ALMNACRBNALDH1A1NPC1 | |
| SCHEMBL10552461 | 0.91 | RAB9A (0.41) | RAB9ALMNACRBNALDH1A1MAPT | |
| SCHEMBL10553030 | 0.91 | RAB9A (0.42) | RAB9ALMNACRBNALDH1A1MAPT | |
| SCHEMBL10554784 | 0.91 | RAB9A (0.48) | RAB9ALMNACRBNALDH1A1NPC1 | |
| SCHEMBL10554787 | 0.91 | RAB9A (0.48) | RAB9ALMNACRBNALDH1A1NPC1 | |
| SCHEMBL10552678 | 0.90 | RAB9A (0.42) | RAB9ALMNACRBNALDH1A1MAPT | |
| SCHEMBL10552672 | 0.90 | RAB9A (0.42) | RAB9ALMNACRBNALDH1A1MAPT | |
| SCHEMBL10552667 | 0.90 | RAB9A (0.42) | RAB9ALMNACRBNALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215120-B1 | CYCLOHEXANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1989-08-23 | — | — | EP | disclosed |
| US-4846998-A | LIQUID CRYSTALS, ESTERS, NITRILES; ETHERS, HYDROCARBONS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-07-11 | — | — | US | disclosed |