Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10552489 | 0.97 | RAB9A (0.46) | RAB9ACRBNNPC1LMNAMAOA | |
| SCHEMBL10557493 | 0.96 | RAB9A (0.47) | RAB9ACRBNNPC1LMNAMAOA | |
| SCHEMBL10554787 | 0.94 | RAB9A (0.48) | RAB9ACRBNNPC1LMNAMAOA | |
| SCHEMBL10554784 | 0.94 | RAB9A (0.48) | RAB9ACRBNNPC1LMNAMAOA | |
| SCHEMBL10550286 | 0.93 | RAB9A (0.45) | RAB9ACRBNNPC1LMNAMAOA | |
| SCHEMBL10554433 | 0.93 | RAB9A (0.41) | RAB9ACRBNNPC1LMNAMAOA | |
| SCHEMBL10554147 | 0.90 | RAB9A (0.49) | RAB9ACRBNNPC1LMNAMAOA | |
| SCHEMBL10550555 | 0.90 | RAB9A (0.44) | RAB9ACRBNNPC1LMNAMAOA | |
| SCHEMBL10550549 | 0.90 | RAB9A (0.44) | RAB9ACRBNNPC1LMNAMAOA | |
| SCHEMBL10550561 | 0.90 | RAB9A (0.44) | RAB9ACRBNNPC1LMNAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215120-B1 | CYCLOHEXANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1989-08-23 | — | — | EP | disclosed |
| US-4846998-A | LIQUID CRYSTALS, ESTERS, NITRILES; ETHERS, HYDROCARBONS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-07-11 | — | — | US | disclosed |