Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482106 | 0.98 | ALDH1A1 (0.53) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL4206502 | 0.95 | ALDH1A1 (0.48) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL844829 | 0.93 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL5656419 | 0.91 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBSMN1; SMN2MAPT | |
| SCHEMBL19474878 | 0.91 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBSMN1; SMN2MAPT | |
| SCHEMBL11848105 | 0.91 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBSMN1; SMN2MAPT | |
| SCHEMBL28810775 | 0.91 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBSMN1; SMN2MAPT | |
| SCHEMBL812745 | 0.91 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL18191920 | 0.91 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL18191935 | 0.91 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839409-A | ORGANOTIN OR NONTIN METAL SALTS | MORTON THIOKOL, INC. (US) | 1989-06-13 | — | — | US | disclosed |