Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.42 |
| ▸ | RELA | Q04206 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10551354 | 0.97 | PRSS1 (0.44) | KMT2ALMNANPC1CYP1A2CYP3A4 | |
| SCHEMBL10551185 | 0.95 | LMNA (0.49) | KMT2ALMNANPC1CYP1A2CYP3A4 | |
| SCHEMBL10552899 | 0.93 | LMNA (0.47) | KMT2ALMNANPC1CYP1A2CYP3A4 | |
| SCHEMBL10556000 | 0.93 | KMT2A (0.46) | KMT2ALMNANPC1CYP1A2CYP3A4 | |
| SCHEMBL10554555 | 0.92 | PRSS1 (0.50) | KMT2ALMNANPC1CYP1A2CYP3A4 | |
| SCHEMBL10555320 | 0.91 | MAPT (0.42) | KMT2ALMNANPC1CYP1A2CYP3A4 | |
| SCHEMBL10549983 | 0.90 | PRSS1 (0.48) | KMT2ALMNANPC1CYP1A2CYP3A4 | |
| SCHEMBL10550390 | 0.90 | KMT2A (0.49) | KMT2ALMNANPC1CYP1A2CYP3A4 | |
| SCHEMBL10554742 | 0.89 | MGLL (0.42) | KMT2ALMNANPC1CYP1A2CYP3A4 | |
| SCHEMBL10555478 | 0.89 | MAPT (0.42) | KMT2ALMNANPC1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4846998-A | LIQUID CRYSTALS, ESTERS, NITRILES; ETHERS, HYDROCARBONS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-07-11 | — | — | US | disclosed |