SCHEMBL10550430

SCHEMBL10550430

O=C(COc1ccc2ccccc2c1)OCC1CO1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 1/20 0.54
RAB9A P51151 3/20 0.51
HPGD P15428 2/20 0.51
HTT P42858 2/20 0.51
ALDH1A1 P00352 2/20 0.51
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
PPARG P37231 2/20 0.49
NCOA2 Q15596 2/20 0.49
NCOA1 Q15788 2/20 0.49
NCOA3 Q9Y6Q9 2/20 0.49
NPC1 O15118 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
NR2E3 Q9Y5X4 1/20 0.49
NCOR2 Q9Y618 1/20 0.49
GAA P10253 2/20 0.48
MAPT P10636 2/20 0.48
MGLL Q99685 2/20 0.48
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4620895 0.81 ALDH1A1 (0.68) PTPN7HPGDALDH1A1MEN1KMT2A
SCHEMBL30546900 0.81 ALDH1A1 (0.68) PTPN7HPGDALDH1A1MEN1KMT2A
SCHEMBL2527684 0.81 ALDH1A1 (0.68) PTPN7HPGDALDH1A1MEN1KMT2A
SCHEMBL844653 0.81 ALDH1A1 (0.68) PTPN7HPGDALDH1A1MEN1KMT2A
SCHEMBL10350141 0.80 MGLL (0.67) MGLL
Methane SCHEMBL28312499 0.79 ALDH1A1 (0.66) PTPN7HPGDALDH1A1MEN1KMT2A
SCHEMBL10553721 0.77 ALDH1A1 (0.55) HPGDHTTALDH1A1MEN1KMT2A
SCHEMBL19358241 0.77 TRIM24 (0.43) HPGDALDH1A1GAAMAPTMGLL
SCHEMBL27370553 0.77 PTPN7 (0.63) PTPN7RAB9AHPGDHTTALDH1A1
SCHEMBL10349642 0.76 HRH3 (0.50) HPGDALDH1A1KMT2AMAPTMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4841081-A Method of optically resolving a racemate or a diastereomeric mixture of glycidyl compound OSAKA SODA CO., LTD. (JP) 1989-06-20 US claimed
EP-0220887-A1 Method of optically resolving a racemate or a diastereomeric mixture of glycidyl compound Daiso Co., Ltd. (JP) 1987-05-06 EP disclosed