Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PON1 | P27169 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.36 |
| ▸ | ALDH1B1 | P30837 | 2/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598443 | 0.85 | ALDH2 (0.44) | ALDH2KDM4EKMT2AMAPK1THRB | |
| SCHEMBL5903908 | 0.85 | ALDH2 (0.44) | ALDH2KDM4EKMT2AMAPK1THRB | |
| SCHEMBL9277301 | 0.79 | ALDH2 (0.63) | ALDH2KDM4EKMT2AMAPK1THRB | |
| SCHEMBL10789998 | 0.75 | HSD17B3 (0.46) | ALDH2KDM4EKMT2AMAPK1PON1 | |
| SCHEMBL10548888 | 0.72 | ALDH2 (0.45) | ALDH2KDM4EKMT2AMAPK1THRB | |
| SCHEMBL17525029 | 0.67 | ALDH2 (0.59) | ALDH2KDM4EKMT2AMAPK1THRB | |
| SCHEMBL5086676 | 0.65 | PON1 (0.47) | ALDH2KDM4EKMT2AMAPK1PON1 | |
| SCHEMBL1002679 | 0.65 | CYP3A4 (0.49) | ALDH2KDM4EMAPK1THRBHPGD | |
| SCHEMBL27907872 | 0.64 | ALDH2 (0.47) | ALDH2KDM4EMAPK1HPGDTSHR | |
| Hydrochloric Acid SCHEMBL9098003 | 0.64 | ADORA3 (0.48) | ALDH2KDM4EMAPK1THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4868311-A | DETECTION, ISOLATION, PURIFICATION OF NUCLEIC ACIDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0262212-A1 | BIOTINYLATED PSORALENS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1988-04-06 | — | — | EP | disclosed |
| WO-1987005805-A1 | BIOTINYLATED PSORALENS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF (US) | 1987-10-08 | — | — | WO | disclosed |
| US-4169204-A | WATER SOLUBLE, IMPROVED BONDING ABILITY WITH NUCLEIC ACIDS | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1979-09-25 | — | — | US | disclosed |