Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.36 |
| ▸ | ALDH1B1 | P30837 | 2/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5903908 | 0.85 | ALDH2 (0.44) | ALDH2THRBHPGDTSHRALDH1A1 | |
| SCHEMBL10550597 | 0.85 | ALDH2 (0.44) | ALDH2THRBHPGDTSHRALDH1A1 | |
| SCHEMBL9277301 | 0.79 | ALDH2 (0.63) | ALDH2THRBHPGDTSHRALDH1A1 | |
| SCHEMBL698745 | 0.72 | ALDH2 (0.45) | ALDH2THRBHPGDTSHRALDH1A1 | |
| SCHEMBL10548888 | 0.68 | ALDH2 (0.45) | ALDH2THRBHPGDTSHRALDH1A1 | |
| SCHEMBL17525029 | 0.67 | ALDH2 (0.59) | ALDH2THRBHPGDTSHRALDH1A1 | |
| SCHEMBL7000371 | 0.65 | MAOA (0.60) | ALDH2HPGDTSHRALDH1A1KDM4E | |
| SCHEMBL3939905 | 0.65 | KDM4E (0.43) | ALDH2THRBHPGDTSHRALDH1A1 | |
| SCHEMBL1002679 | 0.65 | CYP3A4 (0.49) | ALDH2THRBHPGDTSHRALDH1A1 | |
| SCHEMBL27907872 | 0.64 | ALDH2 (0.47) | ALDH2HPGDTSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104027809-B | Treat the method and system of cell proliferation disorders | 免疫之光有限责任公司 | 2017-08-25 | — | — | CN | disclosed |
| CN-104027809-A | METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS | IMMUNOLIGHT LLC | 2014-09-10 | — | — | CN | disclosed |
| CN-101711246-B | Methods and systems for treating cell proliferative disorders | IMMUNOLIGHT LLC | 2014-06-25 | — | — | CN | disclosed |
| CN-101711246-A | Methods and systems for treating cell proliferative disorders | IMMUNOLIGHT LLC | 2010-05-19 | — | — | CN | disclosed |
| US-20020028455-A1 | Methods and reagents for assembling molecules on solid supports | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2002-03-07 | — | — | US | disclosed |
| WO-2001083826-A2 | METHODS AND REAGENTS FOR ASSEMBLING MOLECULES ON SOLID SUPPORTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-11-08 | — | — | WO | disclosed |
| US-5665541-A | Formation of triple helix complexes for the detection of double stranded DNA sequences using oligomers which comprise an 8-modified purine base | THE JOHNS HOPKINS UNIVERSITY (US) | 1997-09-09 | — | — | US | disclosed |
| US-5514707-A | Inhibition of smooth muscle cell proliferation by 8-methoxypsoralen photoactivated by visible light | YALE UNIVERSITY (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0672171-A1 | FORMATION OF TRIPLE HELIX COMPLEXES OF DOUBLE STRANDED DNA USING NUCLEOSIDE OLIGOMERS WHICH COMPRISE PURINE BASE ANALOGS | THE JOHNS HOPKINS UNIVERSITY (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0650526-A1 | FORMATION OF TRIPLE HELIX COMPLEXES OF SINGLE STRANDED NUCLEIC ACIDS USING NUCLEOSIDE OLIGOMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 1995-05-03 | — | — | EP | disclosed |
| US-5354774-A | Aftertreatment angioplasty | YALE UNIVERSITY (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1993007295-A1 | FORMATION OF TRIPLE HELIX COMPLEXES OF SINGLE STRANDED NUCLEIC ACIDS USING NUCLEOSIDE OLIGOMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 1993-04-15 | — | — | WO | disclosed |
| WO-1993005180-A1 | FORMATION OF TRIPLE HELIX COMPLEXES OF DOUBLE STRANDED DNA USING NUCLEOSIDE OLIGOMERS WHICH COMPRISE PURINE BASE ANALOGS | THE JOHNS HOPKINS UNIVERSITY (US) | 1993-03-18 | — | — | WO | disclosed |
| EP-0266099-A2 | Oligonucleoside alkyl or arylphosphonate derivatives capable of crosslinking with or cleaving nucleic acids | THE JOHNS HOPKINS UNIVERSITY (US) | 1988-05-04 | — | — | EP | disclosed |