Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25366060 | 0.74 | KMT2A (0.39) | SLC6A2SLC6A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL2302832 | 0.71 | SSTR4 (0.48) | GRM2SSTR4SLC6A2SLC6A4TSHR | |
| SCHEMBL27495902 | 0.71 | GRM2 (0.38) | GRM2SSTR4SLC6A2SLC6A4DPP4 | |
| SCHEMBL1397024 | 0.71 | SLC6A4 (0.40) | GRM2SSTR4SLC6A2SLC6A4DPP4 | |
| SCHEMBL2202363 | 0.71 | SSTR4 (0.40) | GRM2SSTR4SLC6A2SLC6A4DPP4 | |
| SCHEMBL2544615 | 0.70 | CHRNA3 (0.68) | SLC6A2SLC6A4CHRNB2CHRNA4 | |
| SCHEMBL1396836 | 0.70 | CHRNA3 (0.68) | SLC6A2SLC6A4CHRNB2CHRNA4 | |
| SCHEMBL2202899 | 0.67 | DPP4 (0.43) | GRM2SLC6A2SLC6A4DPP4PREP | |
| SCHEMBL31071539 | 0.67 | SLC6A2 (0.55) | SSTR4SLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL10552599 | 0.67 | METAP2 (0.40) | GRM2SSTR4METAP2HTR1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826861-A | MEDICAL BACTERICIDES OR FUNGICIDES | ALBERT ROLAND, S.A. (FR) | 1989-05-02 | — | — | US | disclosed |
| US-4647557-A | Novel heterocyclic derivatives bearing an amino radical, processes for their production and the pharmaceutical compositions containing them | MOINET GERARD (FR) | 1987-03-03 | — | — | US | disclosed |