Diethyl Maleate

Diethyl Maleate

SCHEMBL10550992

CC(C)OC(=O)C=CC(=O)OC(C)C.CCOC(=O)C=CC(=O)OCC

nearest known ligand 0.59

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.59
MAPT P10636 7/20 0.44
ATM Q13315 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
AKR1B10 O60218 1/20 0.42
AKR1B1 P15121 1/20 0.42
LMNA P02545 3/20 0.41
MDM2 Q00987 2/20 0.41
MDM4 O15151 1/20 0.41
ALDH1A1 P00352 2/20 0.40
TTR P02766 1/20 0.39
DPP4 P27487 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL992124 1.00 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
SCHEMBL3516777 1.00 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL15751751 1.00 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
SCHEMBL992126 1.00 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
SCHEMBL8416347 0.85 HCAR2 (0.57) HCAR2MAPTATMNPSR1CA12
SCHEMBL8416349 0.85 HCAR2 (0.57) HCAR2MAPTATMNPSR1CA12
Butane SCHEMBL15751306 0.84 HCAR2 (0.67) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL2015896 0.83 HCAR2 (0.80) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL42602 0.83 HCAR2 (0.80) HCAR2MAPTATMNPSR1CA12
SCHEMBL18235510 0.83 HCAR2 (0.55) HCAR2MAPTATMNPSR1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4855374-A Optical resin from diallyl esters NIPPON OIL AND FATS CO., LTD. (JP) 1989-08-08 US claimed
CN-115698786-B Laminated film, polarizing plate and liquid crystal display device 柯尼卡美能达株式会社 2026-05-15 CN disclosed
EP-2738205-B1 RESIN COMPOSITION, OPTICAL COMPENSATION FILM USING SAME, AND METHOD FOR PRODUCING OPTICAL COMPENSATION FILM TOSOH CORP (JP) 2017-05-31 EP disclosed
US-9370901-B2 Resin composition, optical compensation film using the same and production method of optical compensation film TOSOH CORPORATION (JP) 2016-06-21 US disclosed
US-20140153096-A1 RESIN COMPOSITION, OPTICAL COMPENSATION FILM USING THE SAME AND PRODUCTION METHOD OF OPTICAL COMPENSATION FILM TOSOH CORPORATION (JP) 2014-06-05 US disclosed
EP-2738205-A1 RESIN COMPOSITION, OPTICAL COMPENSATION FILM USING SAME, AND METHOD FOR PRODUCING OPTICAL COMPENSATION FILM Tosoh Corporation (JP) 2014-06-04 EP disclosed