SCHEMBL8416347

SCHEMBL8416347

CCOC(=O)/C=C\C(=O)OC(C)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.57
MAPT P10636 6/20 0.43
ATM Q13315 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
LMNA P02545 2/20 0.40
MDM2 Q00987 2/20 0.40
MDM4 O15151 1/20 0.40
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
ALDH1A1 P00352 2/20 0.39
TTR P02766 1/20 0.38
DPP4 P27487 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8416349 1.00 HCAR2 (0.57) HCAR2MAPTATMNPSR1CA12
SCHEMBL992126 0.85 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
SCHEMBL3516777 0.85 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL15751751 0.85 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL10550992 0.85 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
SCHEMBL992124 0.85 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
SCHEMBL2911353 0.84 HCAR2 (0.54) HCAR2ATMCA12CA1CA2
SCHEMBL6835137 0.84 HCAR2 (0.54) HCAR2ATMCA12CA1CA2
SCHEMBL5053871 0.84 HCAR2 (0.54) HCAR2ATMCA12CA1CA2
Diethyl Maleate SCHEMBL135447 0.84 HCAR2 (0.76) HCAR2MAPTATMNPSR1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001892-A (A) UNSATURATED POLYESTER; (B) VINYL ETHER COMPONENT OF GIVEN FORMULA; AND (C) REACTIVE DILUENT COMPRISING AN UNSATURATED DIOIC ESTER OF GIVEN FORMULA, THE DILUENT LOWERS THE INITIAL APPLICATION VISCOSITY WITHOUT INCREASING CURE TIME PPG INDUSTRIES OHO, INC. (US) 1999-12-14 US disclosed
EP-0771331-B1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES INC (US) 1998-08-26 EP disclosed
EP-0771331-A1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES, INC. (US) 1997-05-07 EP disclosed
WO-1996001283-A1 POLYESTER AND VINYL ETHER RADIATION CURABLE COMPOSITIONS WITH REACTIVE DILUENT PPG INDUSTRIES, INC. (US) 1996-01-18 WO disclosed
US-4151149-A OXYGEN BARRIER MEMBRANES, SULFATED MONOMERS UNION OIL COMPANY OF CALIFORNIA (US) 1979-04-24 US disclosed
US-4079025-A ADDITION POLYMER A. E. STALEY MANUFACTURING COMPANY (US) 1978-03-14 US disclosed
US-3951892-A POLYSTYRENE PARTICLES DISPERSED IN NEUTRALIZED MALEINIZED DRYING OIL A. E. STALEY MANUFACTURING COMPANY (US) 1976-04-20 US disclosed
US-3950290-A DISPERSION, WATER SOLUBLE OILS, STYRENE POLYMERS A. E. STALEY MANUFACTURING COMPANY (US) 1976-04-13 US disclosed
US-3946139-A LAMINATES W. R. GRACE & CO. (US) 1976-03-23 US disclosed