SCHEMBL992124

SCHEMBL992124

CCOC(=O)/C=C\C(=O)OC(C)C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.59
MAPT P10636 7/20 0.44
ATM Q13315 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
AKR1B10 O60218 1/20 0.42
AKR1B1 P15121 1/20 0.42
LMNA P02545 3/20 0.41
MDM2 Q00987 2/20 0.41
MDM4 O15151 1/20 0.41
ALDH1A1 P00352 2/20 0.40
TTR P02766 1/20 0.39
DPP4 P27487 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3516777 1.00 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL15751751 1.00 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL10550992 1.00 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
SCHEMBL992126 1.00 HCAR2 (0.59) HCAR2MAPTATMNPSR1CA12
SCHEMBL8416347 0.85 HCAR2 (0.57) HCAR2MAPTATMNPSR1CA12
SCHEMBL8416349 0.85 HCAR2 (0.57) HCAR2MAPTATMNPSR1CA12
Butane SCHEMBL15751306 0.84 HCAR2 (0.67) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL2015896 0.83 HCAR2 (0.80) HCAR2MAPTATMNPSR1CA12
Diethyl Maleate SCHEMBL42602 0.83 HCAR2 (0.80) HCAR2MAPTATMNPSR1CA12
SCHEMBL18235510 0.83 HCAR2 (0.55) HCAR2MAPTATMNPSR1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1753789-B1 DISPERSANT VISCOSITY MODIFIERS BASED ON MALEIC ANHYDRIDE-STYRENE COPOLYMERS LUBRIZOL CORP (US) 2017-06-28 EP disclosed
EP-2451909-B1 POLYMER BLENDS USEFUL AS VISCOSITY MODIFIERS LUBRIZOL CORP (US) 2015-09-16 EP disclosed
EP-2451910-B1 LUBRICANT CONTAINING DISPERSANT VISCOSITY MODIFIERS LUBRIZOL CORP (US) 2015-04-15 EP disclosed
EP-2001983-B1 Lubricating compositions containing a styrene-butadiene diblock copolymer LUBRIZOL CORP (US) 2015-02-18 EP disclosed
US-8778854-B2 Dispersant viscosity modifiers THE LUBRIZOL CORPORATION (US) 2014-07-15 US disclosed
US-8772211-B2 Polymer blends useful as viscosity modifiers THE LUBRIZOL CORPORATION (US) 2014-07-08 US disclosed
US-8354362-B2 Polymer and lubricating compositions thereof THE LUBRIZOL CORPORATION (US) 2013-01-15 US disclosed
US-20120178656-A1 Dispersant Viscosity Modifiers THE LUBRIZOL CORPORATION (US) 2012-07-12 US disclosed
US-20120178659-A1 Dispersant Viscosity Modifiers THE LUBRIZOL CORPORATION (US) 2012-07-12 US disclosed
US-20120157364-A1 Polymer Blends Useful as Viscosity Modifiers THE LUBRIZOL CORPORATION (US) 2012-06-21 US disclosed
EP-0203991-A1 POLYMERIC COMPOSITIONS, OIL COMPOSITIONS CONTAINING SAID POLYMERIC COMPOSITIONS, TRANSMISSION FLUIDS AND HYDRAULIC FLUIDS. LUBRIZOL CORP (US) 1986-12-10 EP disclosed
EP-0201597-A1 AMINO SULFONIC ACID DERIVATIVES OF CARBOXYLIC ACID-CONTAINING INTERPOLYMERS, AND FUELS, LUBRICANTS AND AQUEOUS SYSTEMS CONTAINING SAID DERIVATIVES The Lubrizol Corporation (US) 1986-11-20 EP disclosed
US-4620855-A EMULSIFIERS, THICKENERS, DISPERSANTS THE LUBRIZOL CORP. (US) 1986-11-04 US disclosed
WO-1986004338-A1 ESTERS OF CARBOXY-CONTAINING INTERPOLYMERS THE LUBRIZOL CORPORATION (US) 1986-07-31 WO disclosed
US-4594378-A Blend of oil soluble homopolymer of non-aromatic mono-olefin and nitrogen-containing ester of a carboxy containing interpolymer THE LUBRIZOL CORPORATION (US) 1986-06-10 US disclosed
WO-1986003221-A1 POLYMERIC COMPOSITIONS, OIL COMPOSITIONS CONTAINING SAID POLYMERIC COMPOSITIONS, TRANSMISSION FLUIDS AND HYDRAULIC FLUIDS THE LUBRIZOL CORPORATION (US) 1986-06-05 WO disclosed
WO-1986002941-A1 AMINO SULFONIC ACID DERIVATIVES OF CARBOXYLIC ACID-CONTAINING INTERPOLYMERS, AND FUELS, LUBRICANTS AND AQUEOUS SYSTEMS CONTAINING SAID DERIVATIVES THE LUBRIZOL CORPORATION (US) 1986-05-22 WO disclosed
US-4389334-A ACRYLIC COPOLYMER MODIFIED WITH ALKALINE EARTH HALIDE THE STANDARD OIL COMPANY (US) 1983-06-21 US disclosed
US-4289668-A ACRYLIC COPOLYMER; MOLDING MATERIALS HAVING GOOD PROCESSABILITY THE STANDARD OIL COMPANY (US) 1981-09-15 US disclosed
US-4284414-A Mixed alkyl esters of interpolymers for use in crude oils THE LUBRIZOL CORPORATION (US) 1981-08-18 US disclosed