Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28988046 | 0.74 | MCL1 (0.41) | ACP1MEN1KMT2A | |
| SCHEMBL10595746 | 0.71 | ACP1 (0.38) | ACP1 | |
| SCHEMBL4804259 | 0.70 | — | — | |
| SCHEMBL23929057 | 0.70 | ACP1 (0.38) | ACP1MEN1KMT2A | |
| SCHEMBL9026434 | 0.69 | — | — | |
| SCHEMBL433587 | 0.69 | — | — | |
| SCHEMBL7742819 | 0.68 | KDM4E (0.33) | — | |
| SCHEMBL7747110 | 0.67 | — | — | |
| SCHEMBL27793185 | 0.67 | ACP1 (0.39) | ACP1 | |
| SCHEMBL2722596 | 0.66 | TGFBR1 (0.38) | ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839352-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-06-13 | — | — | US | claimed |
| US-4424230-A | CARBAPENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1984-01-03 | — | — | US | claimed |
| US-4232030-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-11-04 | — | — | US | claimed |
| US-4226870-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | claimed |
| EP-0001265-A1 | O-, N- and carboxyl derivatives of thienamycin sulfoxide and sulfone, their preparation and pharmaceuticals containing said compounds | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | claimed |
| EP-0001264-A1 | Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | claimed |
| US-4839352-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0134301-A1 | 6-(1'-Hydroxyethyl)-3-substituted amino-1-azabicyclo(3.2.0)-hept-2-en-7-one-2-carboxylic acid | MERCK & CO. INC. (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4465687-A | ANTIARTHRITIC AGENT, ENZYME INHIBITOR | MERCK & CO., INC. (US) | 1984-08-14 | — | — | US | disclosed |
| US-4424230-A | CARBAPENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1984-01-03 | — | — | US | disclosed |
| US-4397861-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1983-08-09 | — | — | US | disclosed |
| US-4335043-A | Substituted N-methylene derivatives of thienamycin | MERCK & CO., INC. (US) | 1982-06-15 | — | — | US | disclosed |
| US-4318912-A | 6-(1-Hydroxyethyl)-3-substituted-1-azabicyclo(3.2.0)-hept-2-en-7-one-2-carboxylic acid | MERCK & CO., INC. (US) | 1982-03-09 | — | — | US | disclosed |
| US-4226870-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4208330-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1980-06-17 | — | — | US | disclosed |
| US-4194047-A | Substituted N-methylene derivatives of thienamycin | MERCK & CO., INC. (US) | 1980-03-18 | — | — | US | disclosed |
| US-4172144-A | Schiff's base derivatives of thienamycin | MERCK & CO., INC. (US) | 1979-10-23 | — | — | US | disclosed |
| US-4150145-A | ANTIBIOTIC, BACTERICIDES | MERCK & CO., INC. (US) | 1979-04-17 | — | — | US | disclosed |
| EP-0001264-A1 | Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |
| EP-0001265-A1 | O-, N- and carboxyl derivatives of thienamycin sulfoxide and sulfone, their preparation and pharmaceuticals containing said compounds | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |