Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11780925 | 0.80 | PPARG (0.43) | PPARGPPARASMN1; SMN2HIF1ALTA4H | |
| SCHEMBL14461582 | 0.77 | SLC6A2 (0.56) | SLC6A2TAAR1PPARGPPARACYP1A2 | |
| SCHEMBL1357067 | 0.76 | PPARG (0.50) | SLC6A2TAAR1PPARGPPARACYP1A2 | |
| SCHEMBL11784473 | 0.74 | TSHR (0.43) | SLC6A2PPARGCYP1A2CYP2C19LMNA | |
| SCHEMBL1357068 | 0.74 | PPARG (0.49) | SLC6A2TAAR1PPARGPPARACYP1A2 | |
| SCHEMBL6670077 | 0.73 | ALDH1A1 (0.44) | TAAR1PPARGPPARACYP2C9CYP2C19 | |
| SCHEMBL5088767 | 0.73 | SLC6A2 (0.50) | SLC6A2TAAR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5031081 | 0.73 | LTA4H (0.39) | TAAR1CYP2C9CYP2C19LMNATSHR | |
| SCHEMBL30462272 | 0.73 | CYP2C9 (0.53) | SLC6A2TAAR1PPARGPPARACYP1A2 | |
| SCHEMBL28381133 | 0.71 | KCNA3 (0.48) | TAAR1CYP2C9CYP2C19LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839352-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-06-13 | — | — | US | claimed |