Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10559724 | 0.96 | HTR2A (0.56) | HTR2AHRH3DRD2TMEM97SIGMAR1 | |
| SCHEMBL10560937 | 0.95 | HTR2A (0.55) | HTR2ADRD2TMEM97SIGMAR1HTR1A | |
| Oxalic Acid SCHEMBL10460865 | 0.94 | KMT2A (0.56) | HTR2AMEN1HTTKMT2AALDH1A1 | |
| SCHEMBL10560791 | 0.93 | DRD2 (0.57) | HTR2ADRD2TMEM97SIGMAR1HTR1A | |
| SCHEMBL10560903 | 0.91 | TMEM97 (0.56) | MEN1KMT2AHRH3TMEM97SIGMAR1 | |
| Oxalic Acid SCHEMBL10461397 | 0.91 | KDM4E (0.58) | HTR2AMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL10460536 | 0.90 | HTR2A (0.58) | HTR2AMEN1LMNAHTTKMT2A | |
| SCHEMBL10557274 | 0.87 | TMEM97 (0.60) | HTR2AMEN1KMT2AALDH1A1HRH3 | |
| Oxalic Acid SCHEMBL10460451 | 0.87 | DRD2 (0.60) | ALDH1A1DRD2HTR1AHTR7SLC6A3 | |
| Fumaric Acid SCHEMBL10461367 | 0.87 | DRD2 (0.51) | HTR2ADRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | claimed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | claimed |