Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.83 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.83 |
| ▸ | MTOR | P42345 | 3/20 | 0.83 |
| ▸ | RAB9A | P51151 | 3/20 | 0.83 |
| ▸ | TSHR | P16473 | 2/20 | 0.83 |
| ▸ | FAAH | O00519 | 1/20 | 0.83 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 4/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | BLM | P54132 | 3/20 | 0.81 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.81 |
| ▸ | HTR2A | P28223 | 8/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.56 |
| ▸ | HRH1 | P35367 | 8/20 | 0.56 |
| ▸ | DRD3 | P35462 | 8/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amperozide SCHEMBL340961 | 0.91 | CYP3A4 (1.00) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| Amperozide SCHEMBL1321270 | 0.89 | MEN1 (1.00) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| Amperozide SCHEMBL17360644 | 0.88 | CYP3A4 (0.95) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL10557106 | 0.85 | CYP3A4 (0.74) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| Hydrochloric Acid SCHEMBL10510286 | 0.80 | MEN1 (0.83) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL28876807 | 0.79 | CYP3A4 (0.64) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| Hydrochloric Acid SCHEMBL10510024 | 0.79 | KMT2A (0.81) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL4750789 | 0.78 | SLC6A3 (0.64) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL10554386 | 0.78 | SLC6A3 (0.60) | CYP3A4CYP2D6MAPK1MTORRAB9A | |
| SCHEMBL10814470 | 0.78 | CYP3A4 (0.71) | CYP3A4CYP2D6MAPK1MTORRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801706-A | ANTIARRHYTHMIA HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-01-31 | — | — | US | claimed |
| US-4801706-A | ANTIARRHYTHMIA HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |