SCHEMBL28876807

SCHEMBL28876807

CCN1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.64
CYP2D6 P10635 2/20 0.64
FAAH O00519 1/20 0.64
TSHR P16473 1/20 0.64
ALOX12 P18054 1/20 0.64
MAPK1 P28482 1/20 0.64
MTOR P42345 1/20 0.64
RAB9A P51151 1/20 0.64
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
BLM P54132 1/20 0.63
PMP22 Q01453 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
SCN5A Q14524 1/20 0.58
HTR2A P28223 6/20 0.57
ADRA1A P35348 6/20 0.57
HRH1 P35367 6/20 0.57
DRD3 P35462 6/20 0.57
SLC6A3 Q01959 6/20 0.57
OPRK1 P41145 5/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9516792 0.89 CYP3A4 (0.63) CYP3A4CYP2D6FAAHTSHRALOX12
SCHEMBL10362364 0.84 HTR2A (0.61) CYP3A4CYP2D6FAAHTSHRALOX12
SCHEMBL10334811 0.84 SCN5A (0.58) CYP3A4CYP2D6FAAHTSHRALOX12
SCHEMBL14244177 0.83 CYP3A4 (0.56) CYP3A4CYP2D6FAAHTSHRALOX12
SCHEMBL7634586 0.83 SCN5A (0.59) CYP3A4CYP2D6FAAHTSHRALOX12
SCHEMBL7295696 0.81 SCN5A (0.58) CYP3A4CYP2D6FAAHTSHRALOX12
SCHEMBL2268114 0.81 SIGMAR1 (0.58) CYP3A4CYP2D6FAAHTSHRALOX12
SCHEMBL10556025 0.81 SCN5A (0.58) CYP3A4CYP2D6FAAHTSHRALOX12
SCHEMBL11338768 0.81 SIGMAR1 (0.58) CYP3A4CYP2D6FAAHTSHRALOX12
Hydrochloric Acid SCHEMBL10947777 0.81 MEN1 (0.73) CYP3A4CYP2D6FAAHTSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106471373-B For treating, diagnosing and the method for prognosis Malignancy 约瑟卡雷拉斯白血球过多症研究所 2019-08-23 CN disclosed