Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10557099 | 0.97 | ALDH1A1 (0.60) | KDM4EMEN1ALDH1A1KMT2AABCB11 | |
| SCHEMBL10461124 | 0.91 | ABCB11 (0.59) | KDM4EMEN1ALDH1A1KMT2AABCB11 | |
| SCHEMBL10556085 | 0.89 | ALDH1A1 (0.62) | KDM4EMEN1ALDH1A1KMT2AABCB11 | |
| Oxalic Acid SCHEMBL10558729 | 0.87 | MEN1 (0.65) | KDM4EMEN1ALDH1A1KMT2AABCB11 | |
| SCHEMBL7436796 | 0.84 | KCNH2 (0.50) | KDM4EMEN1ALDH1A1KMT2AABCB11 | |
| SCHEMBL10556891 | 0.84 | ABCB11 (0.57) | KDM4EMEN1ALDH1A1KMT2AABCB11 | |
| SCHEMBL9032340 | 0.83 | KDM4E (0.60) | KDM4EMEN1ALDH1A1KMT2AABCB11 | |
| SCHEMBL10557712 | 0.83 | MEN1 (0.49) | KDM4EMEN1ALDH1A1KMT2AABCB11 | |
| Oxalic Acid SCHEMBL10459168 | 0.82 | ALDH1A1 (0.59) | KDM4EMEN1ALDH1A1KMT2AABCB11 | |
| SCHEMBL10557326 | 0.81 | MEN1 (0.57) | KDM4EMEN1ALDH1A1KMT2AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | claimed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | claimed |