Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10559380 | 0.85 | CYP19A1 (0.41) | CYP19A1SLC6A4SLC6A3MAPTSLC6A2 | |
| SCHEMBL10556268 | 0.85 | CYP19A1 (0.47) | CYP19A1SLC6A4SLC6A3CYP3A4CYP3A5 | |
| SCHEMBL10968603 | 0.83 | CYP19A1 (0.51) | CYP19A1LMNATP53HTTIDO1 | |
| SCHEMBL10562484 | 0.81 | ALPL (0.45) | CYP19A1SLC6A4SLC6A3MEN1MAPT | |
| SCHEMBL10967991 | 0.81 | SMN1; SMN2 (0.53) | CYP19A1LMNAIDO1TDO2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11192967 | 0.81 | CYP19A1 (0.50) | CYP19A1LMNAIDO1TDO2SLC6A4 | |
| SCHEMBL2010111 | 0.80 | IDO1 (0.60) | LMNATP53HTTIDO1TDO2 | |
| SCHEMBL3832267 | 0.78 | CYP19A1 (0.68) | CYP19A1SLC6A4SLC6A3CYP3A4CYP3A5 | |
| SCHEMBL10688955 | 0.78 | CYP19A1 (0.46) | CYP19A1LMNATP53HTTIDO1 | |
| SCHEMBL3652018 | 0.78 | CYP19A1 (0.46) | CYP19A1LMNAIDO1TDO2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874775-A | INHIBIT PHYTOPATHOGENS | ELI LILLY AND COMPANY (US) | 1989-10-17 | — | — | US | disclosed |
| EP-0206581-A2 | Agriculturally-useful sulfonamides | ELI LILLY AND COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |
| CN-86103621-A | The method of the sulphonamide of preparation agriculturally useful | — | 1986-12-10 | — | — | CN | disclosed |