Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 9/20 | 0.80 |
| ▸ | DRD3 | P35462 | 9/20 | 0.80 |
| ▸ | HTR2A | P28223 | 8/20 | 0.80 |
| ▸ | HRH1 | P35367 | 8/20 | 0.80 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.80 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.80 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.80 |
| ▸ | DRD2 | P14416 | 6/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.80 |
| ▸ | MEN1 | O00255 | 4/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.80 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.80 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.80 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.80 |
| ▸ | HTR2B | P41595 | 4/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lidoflazine SCHEMBL79037 | 0.89 | ADRA1A (1.00) | ADRA1ADRD3HTR2AHRH1SLC6A3 | |
| SCHEMBL10554577 | 0.87 | HTR2A (0.71) | ADRA1ADRD3HTR2AHRH1SLC6A3 | |
| SCHEMBL79038 | 0.83 | MEN1 (0.88) | ADRA1ADRD3HTR2AHRH1SLC6A3 | |
| SCHEMBL10683725 | 0.79 | ADRA1A (0.76) | ADRA1ADRD3HTR2AHRH1SLC6A3 | |
| Lidoflazine SCHEMBL28086565 | 0.79 | ADRA1A (0.71) | ADRA1ADRD3HTR2AHRH1SLC6A3 | |
| SCHEMBL10676648 | 0.78 | ADRA1A (0.73) | ADRA1ADRD3HTR2AHRH1SLC6A3 | |
| Hydrochloric Acid SCHEMBL10675752 | 0.76 | ADRA1A (0.71) | ADRA1ADRD3HTR2AHRH1SLC6A3 | |
| SCHEMBL10676097 | 0.76 | ADRA1A (0.70) | ADRA1ADRD3HTR2AHRH1SLC6A3 | |
| SCHEMBL10559545 | 0.75 | CYP3A4 (0.58) | ADRA1ADRD3HTR2AHRH1SLC6A3 | |
| Cadaverine Tartrate SCHEMBL10675929 | 0.74 | ADRA1A (0.68) | ADRA1ADRD3HTR2AHRH1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801706-A | ANTIARRHYTHMIA HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |