Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10560151 | 0.92 | MAPT (0.39) | MAPTKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL10561445 | 0.88 | GRM5 (0.37) | MAPTKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL10558285 | 0.88 | GABRP (0.42) | MAPTKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL10558290 | 0.88 | GABRP (0.42) | MAPTKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL10560746 | 0.87 | GRM5 (0.35) | MAPTKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL7297596 | 0.81 | MAPT (0.38) | MAPTKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL7288991 | 0.78 | GABRP (0.40) | MAPTKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL10564163 | 0.78 | CA12 (0.35) | MAPTKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL9191920 | 0.78 | GRM5 (0.36) | MAPTKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL10367467 | 0.78 | MAPT (0.44) | MAPTKMT2AHTTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843075-A | ANXIOLYTIC | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-06-27 | — | — | US | claimed |
| EP-0252990-A1 | BENZOTHIOPYRANO(4,3-C)PYRIDAZINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-20 | — | — | EP | claimed |
| US-4843075-A | ANXIOLYTIC | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0252990-A1 | BENZOTHIOPYRANO(4,3-C)PYRIDAZINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-20 | — | — | EP | disclosed |