Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297596 | 0.92 | MAPT (0.38) | GRM5LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL10561445 | 0.90 | GRM5 (0.37) | GRM5LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7288991 | 0.86 | GABRP (0.40) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10560746 | 0.84 | GRM5 (0.35) | GRM5LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL10365659 | 0.81 | GRM5 (0.38) | GRM5LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL10560151 | 0.81 | MAPT (0.39) | GRM5LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7289927 | 0.78 | ALDH1A1 (0.36) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7288749 | 0.78 | GRM5 (0.36) | GRM5LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL10558366 | 0.78 | MAPT (0.42) | GRM5LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7298595 | 0.77 | PDE4A (0.38) | LMNAMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487768-B1 | Pharmaceutical composition with improved dissolution property | YOSHITOMI PHARMACEUTICAL (JP) | 1995-01-25 | — | — | EP | claimed |
| EP-0487768-A1 | Pharmaceutical composition with improved dissolution property | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-03 | — | — | EP | claimed |
| EP-0487768-B1 | Pharmaceutical composition with improved dissolution property | YOSHITOMI PHARMACEUTICAL (JP) | 1995-01-25 | — | — | EP | disclosed |
| EP-0487768-A1 | Pharmaceutical composition with improved dissolution property | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-03 | — | — | EP | disclosed |