Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.46 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 5/20 | 0.38 |
| ▸ | G6PD | P11413 | 2/20 | 0.38 |
| ▸ | CCR6 | P51684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679729 | 0.81 | CDC25A (0.40) | IDO1MAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL28623338 | 0.71 | HTR2C (0.43) | IDO1DNMT1DNMT3LDNMT3ARAF1 | |
| SCHEMBL263979 | 0.68 | HTR2C (0.42) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL916442 | 0.67 | IDO1 (0.52) | IDO1DNMT1DNMT3LDNMT3ARAF1 | |
| Hydrochloric Acid SCHEMBL7249716 | 0.67 | HTR2C (0.41) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL11120217 | 0.67 | IDO1 (0.52) | IDO1DNMT1DNMT3LDNMT3ARAF1 | |
| Hydrochloric Acid SCHEMBL10382642 | 0.67 | HTR2C (0.41) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| Anthraquinone SCHEMBL27788192 | 0.67 | MEN1 (0.67) | IDO1DNMT1DNMT3LDNMT3AMAPT | |
| SCHEMBL451612 | 0.66 | SLC18A3 (0.43) | MAPTKMT2AMEN1HPGDKDM4E | |
| SCHEMBL1638075 | 0.66 | SLC18A3 (0.43) | MAPTKMT2AMEN1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829089-A | ANTIINFLAMMATORY, BRONCHODILATOR | AMERICAN CYANAMID COMPANY (US) | 1989-05-09 | — | — | US | disclosed |
| US-4771061-A | Substituted piperazine-1,4-naphthalenediones useful for treating asthma, allergic diseases and/or inflammation | AMERICAN CYANAMID COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| US-4686220-A | Substituted 2-[b-substituted-amino)-ethylamino]-1,4-naphthalenediones for treating asthma, allergic diseases and inflammation in warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1987-08-11 | — | — | US | disclosed |
| EP-0226842-A2 | Substituted 1,4-naphthalenediones, processes for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |