Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 6/20 | 0.55 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | QPCT | Q16769 | 1/20 | 0.52 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.52 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465391 | 0.87 | MAPT (0.52) | S1PR1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| Hydrochloric Acid SCHEMBL10464770 | 0.85 | MAPT (0.50) | S1PR1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL24449229 | 0.84 | ACKR3 (0.54) | S1PR1CYP19A1ACKR3CYP11B1CYP11B2 | |
| SCHEMBL13604350 | 0.82 | MEN1 (0.63) | CYP19A1CYP11B1CYP11B2CYP1A2POLB | |
| SCHEMBL15014091 | 0.77 | GRM4 (0.65) | KDRGRM4HDAC6KCNK3KCNK9 | |
| SCHEMBL7990375 | 0.76 | KDR (0.84) | KDRGRM4HDAC6KCNK3KCNK9 | |
| SCHEMBL4486676 | 0.76 | AGTR2 (0.52) | S1PR1CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL31610004 | 0.75 | NPC1 (0.58) | CYP19A1POLBTBXAS1 | |
| SCHEMBL13006757 | 0.74 | CYP11B1 (0.66) | CYP19A1CYP11B1CYP11B2CYP1A2POLB | |
| SCHEMBL13153532 | 0.74 | GRM4 (0.60) | KDRGRM4HDAC6KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873238-A | ANTIULCER AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-10-10 | — | — | US | disclosed |