Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.64 |
| ▸ | ARG2 | P78540 | 5/20 | 0.44 |
| ▸ | ARG1 | P05089 | 3/20 | 0.44 |
| ▸ | NOS2 | P35228 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL4956653 | 0.94 | GSR (0.74) | GSRARG2ARG1NOS2CYP1A2 | |
| Ornithine Aketoglutarate SCHEMBL27844740 | 0.94 | GSR (0.68) | GSRARG2ARG1NOS2CYP1A2 | |
| Lysine SCHEMBL27690087 | 0.91 | GSR (0.69) | GSRARG2ARG1NOS2CYP1A2 | |
| D-Ornithine SCHEMBL28189466 | 0.88 | GSR (0.55) | GSRTSHRGRIK1SLC1A3SLC1A2 | |
| SCHEMBL79859 | 0.88 | GSR (0.56) | GSRARG2ARG1NOS2CYP1A2 | |
| SCHEMBL198242 | 0.88 | GSR (0.56) | GSRARG2ARG1NOS2CYP1A2 | |
| SCHEMBL2722969 | 0.88 | GSR (0.56) | GSRARG2ARG1NOS2CYP1A2 | |
| SCHEMBL30463729 | 0.86 | GSR (0.54) | GSRARG2ARG1NOS2CYP1A2 | |
| SCHEMBL3423971 | 0.86 | GSR (0.59) | GSRARG2ARG1NOS2CYP1A2 | |
| SCHEMBL259006 | 0.86 | GSR (0.59) | GSRARG2ARG1NOS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861705-A | Method for removing components of biological fluids | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 1989-08-29 | — | — | US | disclosed |
| US-4732811-A | Agarose-polyaldehyde beads and their biological application affinity chromatography, hemoperfusion, cell separation, etc. | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 1988-03-22 | — | — | US | disclosed |