Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.56 |
| ▸ | ARG2 | P78540 | 5/20 | 0.50 |
| ▸ | ARG1 | P05089 | 3/20 | 0.50 |
| ▸ | NOS2 | P35228 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198242 | 1.00 | GSR (0.56) | GSRARG2ARG1NOS2CYP1A2 | |
| SCHEMBL79859 | 1.00 | GSR (0.56) | GSRARG2ARG1NOS2CYP1A2 | |
| SCHEMBL30463729 | 0.98 | GSR (0.54) | GSRARG2ARG1NOS2CYP1A2 | |
| SCHEMBL259006 | 0.93 | GSR (0.59) | GSRARG2ARG1NOS2CYP1A2 | |
| SCHEMBL3423971 | 0.93 | GSR (0.59) | GSRARG2ARG1NOS2CYP1A2 | |
| SCHEMBL17262412 | 0.93 | GSR (0.59) | GSRARG2ARG1NOS2CYP1A2 | |
| SCHEMBL29958570 | 0.91 | GSR (0.57) | GSRARG2ARG1NOS2CYP1A2 | |
| SCHEMBL2599185 | 0.91 | GSR (0.57) | GSRARG2ARG1NOS2CYP1A2 | |
| Ornithine SCHEMBL10560893 | 0.88 | GSR (0.64) | GSRARG2ARG1NOS2CYP1A2 | |
| Lysine SCHEMBL4956653 | 0.86 | GSR (0.74) | GSRARG2ARG1NOS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3794011-A1 | AMINO ACID SALTS OF NICOTINIC ACID MONONUCLEOTIDE AND NICOTINAMIDE MONONUCLEOTIDE AS ANTI-AGEING AGENTS | Jumpstart Fertility Pty Ltd (AU) | 2021-03-24 | — | — | EP | claimed |
| US-20170113993-A1 | ORGANIC ACIDS FROM HOMOCITRATE AND HOMOCITRATE DERIVATIVES | MITSUI & CO., LTD. (JP) | 2017-04-27 | — | — | US | disclosed |
| US-20170113993-A1 | ORGANIC ACIDS FROM HOMOCITRATE AND HOMOCITRATE DERIVATIVES | MITSUI & CO., LTD. (JP) | 2017-04-27 | — | — | US | disclosed |
| EP-2632895-A1 | HIV PROTEASE INHIBITORS | Merck Canada Inc. (CA) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012055031-A1 | HIV PROTEASE INHIBITORS | MERCK CANADA INC. (CA) | 2012-05-03 | — | — | WO | disclosed |
| US-4284766-A | Process for the preparation of cephalosporin compounds | GLAXO GROUP LIMITED (GB) | 1981-08-18 | — | — | US | disclosed |
| US-4284767-A | Process for preparing 3-carbamoyloxymethyl cephalosporins | GLAXO GROUP LIMITED (GB) | 1981-08-18 | — | — | US | disclosed |
| US-4258183-A | Process for the preparation of cephalosporin compounds | GLAXO GROUP LIMITED (GB) | 1981-03-24 | — | — | US | disclosed |
| US-4252974-A | Cephalosporin compounds | GLAXO GROUP LIMITED (GB) | 1981-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170113993-A1 | ORGANIC ACIDS FROM HOMOCITRATE AND HOMOCITRATE DERIVATIVES | HOGA1, FABP4, HAGH | GSR 834/4885ARG2 1170/4885ARG1 3868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.