Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1135905 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HPGDMEN1 | |
| SCHEMBL30367918 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HPGDMEN1 | |
| SCHEMBL10229496 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1GPR35HPGD | |
| SCHEMBL10693919 | 0.81 | TSHR (0.49) | ALDH1A1TSHRTDP1GPR35HPGD | |
| Bromide SCHEMBL28506426 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1HPGDMEN1 | |
| SCHEMBL6278459 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1GPR35HPGD | |
| SCHEMBL425736 | 0.80 | GPR35 (0.58) | ALDH1A1TSHRTDP1GPR35HPGD | |
| SCHEMBL7079985 | 0.80 | TDP1 (0.58) | ALDH1A1TSHRTDP1GPR35HPGD | |
| SCHEMBL2416170 | 0.79 | TDP1 (0.50) | ALDH1A1TSHRTDP1GPR35HPGD | |
| SCHEMBL11211677 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1GPR35HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678311-A | Arylcarbonyl derivatives useful as therapeutic agents | NOVO NORDISK AS (DK) | 2005-10-05 | — | — | CN | disclosed |
| CN-1495173-A | Alpha-amino-N-allylamidinonitrobenzene compound and its synthesis | 伊斯曼柯达公司 | 2004-05-12 | — | — | CN | disclosed |
| US-4847367-A | PHOTOSTABILIZERS, CHEMICAL INTERMEDIATE | CIBA-GEIGY CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| CN-86104807-A | Carbonylation method | — | 1987-02-25 | — | — | CN | disclosed |
| US-4512929-A | POLYURETHANE MONOMERS, PLANT SAFENING AGENT | BASF AKTIENGESELLSCHAFT (DE) | 1985-04-23 | — | — | US | disclosed |